DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3649 and CG3036

DIOPT Version :9

Sequence 1:	NP_611725.2	Gene:	CG3649 / 37626	FlyBaseID:	FBgn0034785	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster

Alignment Length:	503	Identity:	146/503 - (29%)
Similarity:	237/503 - (47%)	Gaps:	69/503 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 KGPMWGVRHL----QVLFL--FLCATLIVAQRFNMSVAIVAF-----------------TNANS- 51
            ||.:..||:.    |||.|  .|...|..|.|.|:::|||..                 |.|||
  Fly     6 KGGLQRVRNFLSCRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNSTAANST 70

  Fly    52 SNPN----YPE-YRLTEPQKSYTISSPFWGSCCTQMMSGYLSSRFGAKVLLLTIMLLTALLSIAT 111
            ::|:    |.| :.....|.::.:...|||...|::..|.|:...|.:.:....||..:||::.|
  Fly    71 ASPDGVDVYEERFPWDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWASLLTLIT 135

  Fly   112 PFALAWGGWQLLFWVRFVQGLAMGGMWPCLYTHLAKWCPKKEANR-MGGIMTTGLDCGTIMGFAL 175
            |.| |...:.:|..||.|.|..:|..||.::...|.|.|..|.:: |..:|.:.|  |..:...:
  Fly   136 PLA-AHINYVVLIVVRVVLGFMLGASWPAIHPVAAVWIPPMERSKFMSNMMASSL--GAAITMPI 197

  Fly   176 SGVLSASPLGWPSTFYVPGYLGIVWCLTFLRYGANSPSESKFISLAERKHIQFALEQNQVIRGAT 240
            .|.| .|..||.|.||:.|.:|::|.|.:..:...:|:....||..||:.|:.|:       |.|
  Fly   198 CGYL-ISVAGWASVFYLTGAVGLLWSLAWFTFVYETPATHPRISAEERREIEEAI-------GTT 254

  Fly   241 PP------VPWLQILTSRPFIVLAFCKMSQACSFYTLMQQIPRYIHGIFHYSIAANALLSALP-- 297
            ..      |||.|:|.|.....:..|.......|:|::.|:|.::..|.|:.|..|.|.|:||
  Fly   255 TSKKRPSHVPWGQLLCSPAVWAIIICHGLAVFGFFTVVNQLPTFMSKILHFDIKQNGLFSSLPYL 319

  Fly   298 --FVVMLMSSYGFIFLAEYLTRRRDISLPILRKTINSFATWTPAVALVI---LSYVSDQNVVGSM 357
              :|:.:.|||    ||:||.::..:|....||...:||...|.:.:::   |.|.:..:|  ::
  Fly   320 GKYVMAVASSY----LADYLRKKGTLSTTATRKLFTTFALVIPGLLMIVQVFLGYDATWSV--TI 378

  Fly   358 FCL-IAATAAISGQAIGSSLNHVDLSPNFAGLLFGMSNTLMSAAGVISPIVIGLTVTKESDRSQW 421
            |.| :.|..|::...:|   |.:|::|||.|.:||::|||.|..|.:|..::|....|:.....|
  Fly   379 FSLALFAHGAVTAGYLG---NGLDIAPNFGGTIFGLANTLSSFGGFLSTSMVGALTYKDQSFHSW 440

  Fly   422 RTVFLGISVILFLGNLMYLIFGQMTVQSWNDSP-----SKETETEASP 464
            :.||..::.......:::.|.|...:|.||:.|     |..|:.|..|
  Fly   441 QIVFWILAATYISAAVVFAILGSGELQPWNNPPERVRISDVTQEEGVP 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3649	NP_611725.2	MFS	22..442	CDD:119392	131/459 (29%)
CG3649	NP_611725.2	2A0114euk	23..458	CDD:129972	137/479 (29%)
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	138/477 (29%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	113/397 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.970