DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3649 and Slc17a4

DIOPT Version :9

Sequence 1:	NP_611725.2	Gene:	CG3649 / 37626	FlyBaseID:	FBgn0034785	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_795990.2	Gene:	Slc17a4 / 319848	MGIID:	2442850	Length:	492	Species:	Mus musculus

Alignment Length:	472	Identity:	131/472 - (27%)
Similarity:	220/472 - (46%)	Gaps:	48/472 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 VRHLQVLFLFLCATLIVAQRFNMSVAIVAFT---------NANSSNP---------------NYP 57
            :||.....|.||...|..|:.|:|.||.|..         ||::..|               ..|
Mouse    32 LRHGLAFILHLCNFSIYTQQMNLSFAITAMVNTTVASSQLNASTERPPTNSQDVWNETLQESKAP 96

  Fly    58 EYRLTEPQKSYTISSPFWGSCCTQMMSGYLSSRFGAKVLLLTIMLLTALLSIATPFALAWGGWQL 122
            .|..|...:...:||..:||....:.:||::..||||.::...:|::::|::..|.| |..|..|
Mouse    97 VYDWTPEIQGILLSSLSYGSFIAPIPTGYVAGVFGAKYVVGLGLLISSVLTLFIPLA-ADAGVAL 160

  Fly   123 LFWVRFVQGLAMGGMWPCLYTHLAKWCPKKEANRMGGIMTTGLDCGTIMGFALSGVLSASPLGWP 187
            |..:|.:||:|...:....|:..|||.|.:|.:::..|..:|...||.: ..::|.|....||||
Mouse   161 LIVLRVIQGMAQVMVLTGQYSLWAKWAPPQERSQLITIAASGSMLGTFL-VLIAGGLICQALGWP 224

  Fly   188 STFYVPGYLGIVWCLTFLRYGANSPSESKFISLAERKHIQFALEQNQVIRGATPPVPWLQILTSR 252
            ..||:.|.:|...||.:.....:.|....|||..||::|..:|.|.....|.:.|:.  .::.|.
Mouse   225 YIFYIFGGIGCACCLLWFPLVYDDPQNHPFISTGERRYITCSLAQEDCSLGWSLPIK--AMVKSL 287

  Fly   253 PFIVLAFCKMSQACSFY---TLMQQIPRYIHGIFHYSIAANALLSALPFVVMLMSSYGFI----- 309
            |...:.   :|..|.::   |:|...|.||..:...::..:.:||||||:      :|.:
Mouse   288 PLWAIV---VSYFCEYWLLSTVMAYTPTYISSVLQANLRDSGILSALPFM------FGCVCIILG 343

  Fly   310 -FLAEYLTRRRDISLPILRKTINSFATWTPAVALVILSYVSDQNVVGSMFCLIAATAAISGQAIG 373
             .||::|..|:.:.|..:||...:......:..|:.|.:|.........|.::::..|....: |
Mouse   344 GLLADFLLSRKILRLVTIRKLFTAVGVLASSGILLPLPWVRSSRSTTMAFLVLSSVFASLCDS-G 407

  Fly   374 SSLNHVDLSPNFAGLLFGMSNTLMSAAGVISPIVIGLTVTKESDRSQWRTVFLGISVILFLGNLM 438
            :.:|.:|::|.:||.|.|:.......||.|:|.|.|..::::|:.. ||.||...:.|..:|.|.
Mouse   408 ALINFLDIAPRYAGFLKGLLQVFSYLAGGIAPTVAGFFISQDSEFG-WRNVFFLAAAIDVVGLLF 471

  Fly   439 YLIFGQMTVQSWNDSPS 455
            ||||.:..||.|...|:
Mouse   472 YLIFSRAEVQDWAKEPT 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3649	NP_611725.2	MFS	22..442	CDD:119392	123/452 (27%)
CG3649	NP_611725.2	2A0114euk	23..458	CDD:129972	129/466 (28%)
Slc17a4	NP_795990.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		2A0114euk	27..486	CDD:129972	130/468 (28%)
		MFS	98..475	CDD:119392	109/391 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838720
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740