DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3649 and SPAC1002.16c

DIOPT Version :9

Sequence 1:	NP_611725.2	Gene:	CG3649 / 37626	FlyBaseID:	FBgn0034785	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_593504.1	Gene:	SPAC1002.16c / 2543262	PomBaseID:	SPAC1002.16c	Length:	499	Species:	Schizosaccharomyces pombe

Alignment Length:	492	Identity:	109/492 - (22%)
Similarity:	184/492 - (37%)	Gaps:	83/492 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 VLFLFLCATLIVAQRFNMSVAIVAFTNANSSNPNYPEYRLTEPQKSYTISSPFWGS-CCTQMMSG 85
            ::.|:|.|.|   .|.|:..|.||         ..||....:..:...|:|.|:.: ...:|.:.
pombe    63 IMILYLVAFL---DRSNIGNAKVA---------GLPEDLKLKGDQFNIIASVFYVTFILFEMPTT 115

  Fly    86 YLSSRFGAKVLLLTIMLLTALLSIATPFALAWGGWQLLFWVRFVQGLAMGGMWPCLYTHLAKWCP 150
            .|..:...|.:|..|::..:|.:|.|.|...:||   |...|.|.|....|::|||..:|.....
pombe   116 LLMKKVQPKRMLAFIVISYSLTTIFTGFCHNFGG---LLAARLVLGFCEAGLFPCLALYLTMIYS 177

  Fly   151 KKE-ANRMGGIMTTGLDCGTIMGFALSGVLSASPL----GWPSTFYVPGYLGIVWCLTFLRYGAN 210
            :.| |.|:..:..:....|...|.....||....:    ||...|.:.|.:|.|..:.......|
pombe   178 RVELAPRIAYLFASSALSGAFGGLFAYAVLHMDGVGGFAGWRWLFIIEGLIGFVCGVAVYFIIPN 242

  Fly   211 SPSESKFISLAERKHIQFALEQNQVIRGA---TPPVPWLQI---LTSRPFIVLAFCKMSQACSFY 269
            ..:::.|:|    |..|..:.:.|:.|.|   .....|..:   .|.....:.|..:..|....|
pombe   243 DITKAWFLS----KTHQEMMRKRQLERAADLEAAHFDWKGVKSAFTDFKVYLYALSEFGQDTCLY 303

  Fly   270 TLMQQIPRYIHGIFHYSIAANALLSALPFVVMLMSSYGFIFLAEYLTRR---RDISLPILRKTIN 331
            .....:|..|.|:.:.|::...:  .:|..::..::|   ..|.:|:.|   |.|.|.|    .|
pombe   304 GFSTFLPAIISGMGYTSLSVQYM--TIPVYILGAATY---IAASFLSDRFHHRGIILII----GN 359

  Fly   332 SFATWTPAVALVILSYVSDQNVVGSMFCLIAATAAISGQAIGSSLNHVDLSPNFA---------G 387
            .|    |.|..::|....:...|....|.:.:.    |...|:.||...||.|.|         .
pombe   360 IF----PIVGYILLLACQNNKSVLYFACYLCSV----GVYTGAGLNVTWLSANIAPHYKRATAIS 416

  Fly   388 LLFGMSNTLMSAAGVI---SPIVIGLTVTKESDRSQWRTVFLGISVILFLGNLMYLIFGQMTVQS 449
            |...::|:....||.|   .|..|...:|.        .:.:.||.:|.:.|:.:|.. |.:.:.
pombe   417 LQLAIANSSGILAGQIYRYPPKYIAGHLTS--------LIAIFISTVLHVVNIFFLKH-QNSKKQ 472

  Fly   450 WNDSPSKETETEASPKPQASAPSVAEETISVERFNYL 486
            .:.:.|...:....||....|           ||:|:
pombe   473 KSLASSSTIDLSEQPKDDKDA-----------RFHYI 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3649	NP_611725.2	MFS	22..442	CDD:119392	101/446 (23%)
CG3649	NP_611725.2	2A0114euk	23..458	CDD:129972	103/461 (22%)
SPAC1002.16c	NP_593504.1	MFS	63..455	CDD:119392	98/435 (23%)
SPAC1002.16c	NP_593504.1	2A0114	65..435	CDD:273326	93/405 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050