DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3649 and SPAC11D3.18c

DIOPT Version :9

Sequence 1:	NP_611725.2	Gene:	CG3649 / 37626	FlyBaseID:	FBgn0034785	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_001342807.1	Gene:	SPAC11D3.18c / 2543005	PomBaseID:	SPAC11D3.18c	Length:	498	Species:	Schizosaccharomyces pombe

Alignment Length:	474	Identity:	101/474 - (21%)
Similarity:	173/474 - (36%)	Gaps:	135/474 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 FLFLCATL------------------IVAQRFNMSVAIVAFTNANSSNPNYPEYRLTEPQKSYTI 70
            ||:|.|.|                  :..:|.|::|:|.           |..|.|.|
pombe    67 FLYLMAFLDRSNIGNAAVAGMTEALSLYGERLNVAVSIF-----------YVLYILVE------- 113

  Fly    71 SSPFWGSCCTQMMSGYLSSRFGAKVLLLTIMLLTALLSIATPFALAWGGWQLLFWVRFVQGLAMG 135
             :|          |..|..|..|..:|..|....::..:.:.|..::||   |...|.:.||..|
pombe   114 -TP----------SVVLVKRIKASRMLAFISFAWSMTVLFSGFMSSYGG---LIATRLILGLLEG 164

  Fly   136 GMWPCLYTHL-AKWCPKKEANRMGGIM-TTGL--DCGTIMGFALSGVLSASPLGWPSTFYVPG-- 194
            .::|.|..:| ..:..|::..|:..:. :.||  ..|.:..:||..|.:.:..||...:.|.|
pombe   165 CLFPALNLYLTTHYTRKEQCQRLSYLFASAGLAGAFGGLFAYALEQVHAGNKEGWQWIYIVEGLV 229

  Fly   195 -YLGIVWCLTFLRYGANSPSESKFISLAERK------------HIQFALEQNQVIRGATPPVPWL 246
             ::|:..||..|   .:....:.|::..||:            |.:...|.::|.:....|..::
pombe   230 SFIGVPLCLFAL---PDKMENAWFLTREEREVAIIRRDINARYHGEQHFEWSEVRKAFKDPKVYV 291

  Fly   247 QILTSRPFIVLAFCKMSQACS---FYTLMQQIPRYIHGIFHYSIAANALLSALPFVVMLMSSYGF 308
            .             ..||.|:   .|.....:|..|.|:....:..|.:  .:|  |.:.....|
pombe   292 S-------------ATSQFCADMVLYGFSSFLPVIIKGLGFVGLQTNYM--TIP--VYIAGVISF 339

  Fly   309 IFLAEYLTRRRDISLPILRKTINSFATWTPAVALVILSYVSDQNVVGSMFCLIAATAAIS-GQAI 372
            :|:| :|:.|..     ||......|:...||..:|: ..||.|.     ....||..|: |..|
pombe   340 LFVA-WLSDRTQ-----LRAVYLISASTVVAVGYIIM-LASDSNA-----AKYTATYIIAIGCYI 392

  Fly   373 GSSLNHVDLSPNFAG-----LLFGMSNTLMSAAGVIS----------PIVIGLTVTKESDRSQWR 422
            |..||...|:.|.||     ...|:..||.:::|:::          ..::|...|
pombe   393 GPGLNLGWLNNNVAGHYKRATAIGIQQTLANSSGIVAGQIYRSKNAPKYILGNAFT--------- 448

  Fly   423 TVFLGISVILFLGNLMYLI 441
               ||..::   |.|.|::
pombe   449 ---LGCVIV---GGLAYVV 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3649	NP_611725.2	MFS	22..442	CDD:119392	101/474 (21%)
CG3649	NP_611725.2	2A0114euk	23..458	CDD:129972	101/474 (21%)
SPAC11D3.18c	NP_001342807.1	UhpC	68..461	CDD:332119	100/471 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050