DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3649 and Slc17a2

DIOPT Version :9

Sequence 1:	NP_611725.2	Gene:	CG3649 / 37626	FlyBaseID:	FBgn0034785	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	XP_006516709.1	Gene:	Slc17a2 / 218103	MGIID:	2443098	Length:	480	Species:	Mus musculus

Alignment Length:	468	Identity:	127/468 - (27%)
Similarity:	223/468 - (47%)	Gaps:	46/468 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 VRHLQVLFLFLCATLIVAQRFNMSVAIVAFTN-------ANSS-------------------NPN 55
            :|:...|.:......::.||.::|:||:|..|       ||:|                   :..
Mouse    16 LRYALALIMHFSNFTMITQRVSLSIAIIAMVNSTQHQDPANASTEGPVMDLLSNQSRGIKDFSTR 80

  Fly    56 YPEYRLTEPQKSYTISSPFWGSCCTQMMSGYLSSRFGAKVLLLTIMLLTALLSIATPFALAWGGW 120
            ...|:.:...:....||..:|...|.:.||||:..||||.:|...:|:::||::.||.|..: |.
Mouse    81 AAVYQWSTETQGIIFSSISYGIILTLIPSGYLAGIFGAKQILGAGLLISSLLTLFTPLAADF-GV 144

  Fly   121 QLLFWVRFVQGLAMGGMWPCLYTHLAKWCPKKEANRMGGIMTTGLDCGT--IMGFALSGVLSASP 183
            .|:..:|.|||:|.|..|...:|..|||.|..|.:::..|..:|.|.|:  ::...|.|.::.:.
Mouse   145 ILVIVIRTVQGMAQGMAWTGQFTIWAKWAPPLERSKLTSIAGSGEDVGSVWVLHHPLCGRINLTG 209

  Fly   184 LGWPSTFYVPGY-LGIVWCLTFLRYGANSPSESKFISLAERKHIQFALEQNQVIRGATP--PVPW 245
            .|  ..||:... :|.|.|:.:.....:.|.....||:.|::||..::.|    :.::|  .||.
Mouse   210 TG--LAFYLLHLCIGCVCCVLWFTVIYDDPMHHPCISVREKEHITSSVAQ----QSSSPRRSVPI 268

  Fly   246 LQILTSRPF--IVLAFCKMSQACSFYTLMQQIPRYIHGIFHYSIAANALLSALPFVVMLMSSYGF 308
            ..::...|.  |.:.|......|:.  ::..:|.||..:.|.:|..:.:||:|||:.....:...
Mouse   269 KAMVRCLPLWAIFMGFFSHFWLCTI--IITYLPTYISTVLHVNIRDSGVLSSLPFIAASSCTILG 331

  Fly   309 IFLAEYLTRRRDISLPILRKTINSFATWTPAVALVILSYVSDQNVVG-SMFCLIAATAAISGQAI 372
            ..:|::|..|..:||..:||..:|.....|::..|.|.:|:...:.. .:..||..|:.:...
Mouse   332 GQMADFLLSRNLLSLITVRKLFSSLGLLLPSLCAVALPFVTSSYIATIVLLILIPGTSNLCDS-- 394

  Fly   373 GSSLNHVDLSPNFAGLLFGMSNTLMSAAGVISPIVIGLTVTKESDRSQWRTVFLGISVILFLGNL 437
            |..:|.:|::|.:|..|.|:|......||:||....|..::::|: |.||.||...:.:...|.:
Mouse   395 GFIINTLDVAPRYASFLMGISRGFGLTAGIISSTTTGFLISQDSE-SGWRNVFFLSAAVNMFGLI 458

  Fly   438 MYLIFGQMTVQSW 450
            .||||||..:|||
Mouse   459 FYLIFGQAEIQSW 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3649	NP_611725.2	MFS	22..442	CDD:119392	119/453 (26%)
CG3649	NP_611725.2	2A0114euk	23..458	CDD:129972	126/462 (27%)
Slc17a2	XP_006516709.1	MFS_SLC17	21..464	CDD:340876	120/454 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838750
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.750