DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3649 and slc-17.9

DIOPT Version :9

Sequence 1:	NP_611725.2	Gene:	CG3649 / 37626	FlyBaseID:	FBgn0034785	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_001379067.1	Gene:	slc-17.9 / 181189	WormBaseID:	WBGene00011643	Length:	516	Species:	Caenorhabditis elegans

Alignment Length:	483	Identity:	105/483 - (21%)
Similarity:	197/483 - (40%)	Gaps:	60/483 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LFLCATLIVAQRFNMSVAIVAFTNANSSNPNYPEYRLTEP------------------QKSYTIS 71
            |.||...:.....|:|.::|.......:|...|   |.||                  |:....|
Worm    28 LCLCFVALAIGTSNISQSMVCMVKKPDTNYTCP---LAEPEVEAIPCNHPKQFAWSSIQQGLIYS 89

  Fly    72 SPFWGSCCTQMMSGYLSSRFGAKVLLLTIMLLTALLSIATPFALAWGGWQLLFWVRFVQGLAMGG 136
            ...:|| ...:::|:.:.|...|..::..|....:.:...|.: |...:.|:|::|.:.|.....
Worm    90 GQNFGS-LFMVITGWQADRLNGKWTIVAAMAFIIVSNAVLPIS-AGASFALVFFLRVLTGFGDAL 152

  Fly   137 MWPCLYTHLAKWCPKKEANRMGGIMTTGLDCGTIMGFALSGVLSASP-----LGWPSTFYVPGYL 196
            :.|...:.:.:|.|.||.....||:|:|...||::...:.|.|..|.     .|||:.||:...:
Worm   153 LSPASSSLITRWFPPKERPSALGIVTSGRQIGTLIILPIGGWLCGSDGSKFLGGWPAIFYLSSVV 217

  Fly   197 GIVWCLTFLRYGANSPSESKFISLAERKHIQFALEQNQV-IRGATPPVPWLQILTSRPFIVLAFC 260
            .....:.::.:.|:.||:...||..|..:|...:|:..: .|......||..|.||:...|....
Worm   218 AAAVLVIWVVFSADKPSKHLCISHNEEAYINRKIEEENIGKRNNRKNTPWKAIFTSKQVWVAVAA 282

  Fly   261 KMSQACSFYTLMQQIPRYIHGIFHYSIAANALLSALPFVVMLMSSYGFIFLAEYLTRRRDISLPI 325
            .:........::|.:|::...:...|...|.|:||||..::.:|......||.|||..     ..
Worm   283 LVCHEFPLVIMLQFLPKFFSDVLGLSNTVNGLVSALPMAILFLSKCLSASLASYLTAN-----GY 342

  Fly   326 LRKT-----INSFATWTPAVALVILSYVSD-QNVVGS--MFCLIAATAAISGQAIGSSLNHVDLS 382
            ||||     .|..|:....:.:.....:|: |:.:.:  :.||..|.|.:....:.:::  |.|:
Worm   343 LRKTQSCKIFNFIASLGLGICIAATPLMSNLQHAIWAIIILCLANAFAGLHTPGVLTAI--VQLA 405

  Fly   383 PNFAGLLFGMSNTLMSAAGVISPIVIGLTVTKESDRSQWRTVFLGISVILFLGNLMYLIFGQMTV 447
            |.|:|::.|::..:.|...:.:.::|. .:.:...:.:|..||...:.:..|..:.:.::|....
Worm   406 PAFSGIITGLAFAVASCFSIFNKLLIS-QILRTGSKHEWTIVFEISAFVAILPTIFFTLWGSAER 469

  Fly   448 QSW---------------NDSPSKETET 460
            ..|               |||.|..:.|
Worm   470 TEWASNRVSVPKDADQKSNDSGSSTSST 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3649	NP_611725.2	MFS	22..442	CDD:119392	98/448 (22%)
CG3649	NP_611725.2	2A0114euk	23..458	CDD:129972	104/479 (22%)
slc-17.9	NP_001379067.1	2A0114euk	5..474	CDD:129972	100/458 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28615
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920