DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3649 and K11G9.5

DIOPT Version :9

Sequence 1:	NP_611725.2	Gene:	CG3649 / 37626	FlyBaseID:	FBgn0034785	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_504695.2	Gene:	K11G9.5 / 179059	WormBaseID:	WBGene00019655	Length:	460	Species:	Caenorhabditis elegans

Alignment Length:	476	Identity:	105/476 - (22%)
Similarity:	191/476 - (40%)	Gaps:	63/476 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 RHLQVLFLFLCATLIVAQRFNMSVAIV------AFTNANSSNPNYPE--YRLTEPQKSYTISSPF 74
            |.|.|...|||...:.:....|:...:      :||..:..|...|.  :..|..:|.|.:.:..
Worm     9 RVLVVFIGFLCLVSVCSNYVVMNFTFICMKNDMSFTRDDRGNETSPVSLFDYTPNEKKYIMWAVA 73

  Fly    75 WGSCCTQMMSGYLSSRFGAKVLLLTIMLLTALLSIATPFALAWGGWQLLFWVRFVQGLAMGGMWP 139
            .|:........|:..|||.:.......:::.:.:...|.| |...:..|...||.||||....:.
Worm    74 AGTIIGTFPVNYVFVRFGGRWTFFLAGVISVIATTLIPLA-AQTSFHALLAARFCQGLAFAADFA 137

  Fly   140 CLYTHLAKWCPKKEANRMGGIMTTGLDCGTIMGFALSGVLSASPLGWPSTFYVPGYLG----IVW 200
            .:.....:|.|..|.....|.:|:..:..:::..|:||.: ....||.:.||....:|    |:|
Worm   138 AIGLLTVRWAPLSETAIFLGALTSFTNFSSVLTNAVSGAI-CEGFGWRTAFYAHAVMGSVFFILW 201

  Fly   201 CLTFLRYGANSPSESKFISLAERKHIQFALEQNQVIRGATPPVPWLQILTSRPFIVL----AFCK 261
            .:.:     |...|.| :|..|.:.|: ..:..|.::.....||:.::||| |.::.    ||.:
Worm   202 AIVY-----NDDPEKK-VSADELRKIR-KNKSEQHLKTKNVEVPYRKLLTS-PIVLCVWLNAFAE 258

  Fly   262 MSQACSFYTLMQQIPRYIHGIFHYSIAANALLSALP-FVVMLMSSYGFIF--LAEYLTRRRDISL 323
            ||.....:|   ..|.:.:.|..:|:|....|.||. |:.:.:...|.|.  .|:..:.|..:..
Worm   259 MSIIVFLHT---YAPIFFNRILKFSVAQTGFLLALSVFIPLPLKLVGGIISDKAKCFSERGKMLF 320

  Fly   324 PILRKTINSFATWTPAVALVILSYVSDQ---------NVVGSMFCLIAATAAISGQAIGSSLNHV 379
                  .|:.:.....|.|..|.::...         :|:.|..||     .::|....::|:
Worm   321 ------FNTISVGLVGVLLGCLGFIPQSLHYVSVVLFSVIFSCLCL-----NVAGFYKCATLH-- 372

  Fly   380 DLSPNFAGLLFGMSNTLMSAAGVISPIVIGLTVTKESDRSQWRTVFLGISVILFLGNLMYLIFGQ 444
              :..||.::......:.|.|.:..|.::...|..|....|||||...:..|:|:.|::.|..
Worm   373 --TRQFAHVVISTIQWMKSVALITGPALVAAIVKNEESVGQWRTVLCILGGIMFVANILALCV-- 433

  Fly   445 MTVQSWNDSPSKETETEASPK 465
                 :.|.|::.|..:|:.|
Worm   434 -----FTDKPAEYTMADANEK 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3649	NP_611725.2	MFS	22..442	CDD:119392	98/447 (22%)
CG3649	NP_611725.2	2A0114euk	23..458	CDD:129972	99/462 (21%)
K11G9.5	NP_504695.2	MFS	14..429	CDD:391944	96/442 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810