DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3649 and T27D12.1

DIOPT Version :9

Sequence 1:	NP_611725.2	Gene:	CG3649 / 37626	FlyBaseID:	FBgn0034785	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_001254320.1	Gene:	T27D12.1 / 174820	WormBaseID:	WBGene00012085	Length:	502	Species:	Caenorhabditis elegans

Alignment Length:	446	Identity:	92/446 - (20%)
Similarity:	183/446 - (41%)	Gaps:	21/446 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 RHLQVLFLFLCATLIVAQRFNMSVAIVAFTNANSS-----NPNYPEYRLTEPQKSYTISSPFWGS 77
            |.:.::.:.||.|.|.:.....:.|:|...:.:|.     |....:...|..|.|..::.....:
Worm    34 RFVIMVLILLCLTSIWSNILAFNFAVVCMDDDDSEMGASLNGTARKTHFTSTQNSLAMAIVAIAA 98

  Fly    78 CCTQMMSGYLSSRFGAKVLLLTIMLLTALLSIATPFALAWGGWQLLFWVRFVQGLAMGGMWPCLY 142
            .........|....|.:.:...:.:|:|:.::..|.::..|.:..|. |||:||.|....:|.:.
Worm    99 LLGNFPIVQLVGMVGIRTVFAGLGILSAVSTLLIPLSIRMGFYYFLA-VRFLQGFAFAANFPVIG 162

  Fly   143 THLAKWCPKKEANRMGGIMTTGLDCGTIMGFALSGVLSASPLGWPSTFYVPGYLGIVWCLTFLRY 207
            :..|||...|:.......:...:.....:....||.| .|...|||.||..|.:.::..:|:..:
Worm   163 SFCAKWSYFKQNGLFVSSLVAYVQLSPAITMPASGAL-CSAFKWPSIFYAHGAVSLLLFVTYALF 226

  Fly   208 GANSPSESKFISLAERKHIQFALEQNQVIRGATPPVPWLQILTSRPFIVLAFCKMSQACSFYTLM 272
            ..|||.:..|:...|.|.|... :...|.:.|...||:..||.: |.|   :.....|...:|.:
Worm   227 YRNSPQKHPFVGNVELKKISIG-KIAAVDKRALKKVPYGPILKT-PAI---WAVWVAAIGNFTCV 286

  Fly   273 QQI----PRYIHGIFHYSIAANALLSALPFVVMLMSSYGFIFLAEYLTRRRDISLPILRKTINSF 333
            ..:    |.|:..:..:.:.:..:.:|:|..:...|.   :.......|...:|..:..:..|:.
Worm   287 NMMFLFSPIYLSKVLGFPVHSTGITAAIPPFLQFSSK---LICGAASDRLTCLSEGVKFRLFNTL 348

  Fly   334 ATWTPAVALVILSYVSDQNVVGSMFCLIAATAAISGQAIGSSLNHVDLSPNFAGLLFGMSNTLMS 398
            |....|..|.:|:::.|::...:|..|..|.|.:.....|.......||..::..:.|..:..::
Worm   349 AFVGSAGFLCVLAFMGDEHKRNNMIVLGCAAAMLGATTGGFFKAGPVLSKQYSHFVTGNISLGIT 413

  Fly   399 AAGVISPIVIGLTVTKESDRSQWRTVFLGISVILFLGNLMYLIFGQMTVQSW-NDS 453
            ...:|.|..:. .:|..:.:.:|:.|||....::.:.|:.::||.:.....| :||
Worm   414 ITMLIVPFFVN-ALTPNNTQEEWKYVFLITGAVMVITNIFFVIFVRGDPCEWTSDS 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3649	NP_611725.2	MFS	22..442	CDD:119392	86/428 (20%)
CG3649	NP_611725.2	2A0114euk	23..458	CDD:129972	91/441 (21%)
T27D12.1	NP_001254320.1	MFS	56..456	CDD:391944	82/410 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920