Protein Alignment CG3649 and Slc17a6

DIOPT Version :10

• Sequence 1: NP_611725.2
• Gene: CG3649 / 37626
• FlyBaseID: FBgn0034785
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_543129.3
• Gene: Slc17a6 / 140919
• MGIID: 2156052
• Length: 582
• Species: Mus musculus
• Alignment Length: 446
• Identity: 134/446 - (30%)
• Similarity: 225/446 - (50%)
• Gaps: 39/446 - (8%)

  Fly    36 RFNMSVAIVAFTNANS-----------SNPNYPEYRLTEPQKSYTI-SSPFWGSCCTQMMSGYLS 88
            |.|:.||||...|.::           :..|:      :|:....| .|.|||...||:..||::
Mouse    88 RCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNW------DPETVGMIHGSFFWGYIITQIPGGYIA 146

  Fly    89 SRFGAKVLLLTIMLLTALLSIATPFALAWGGWQLLFWVRFVQGLAMGGMWPCLYTHLAKWCPKKE 153
            ||..|..:....:|||:.|::..|.| |...:..:.:||.:|||..|..:|..:...:||.|..|
Mouse   147 SRLAANRVFGAAILLTSTLNMLIPSA-ARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLE 210

  Fly   154 ANRMGGIMTTGLDCGTIMGFALSGVLSASPLGWPSTFYVPGYLGIVWCLTFLRYGANSPSESKFI 218
            .:|:......|...|.::...|:|:| ....||.|.|||.|..|:||.:.:|.....||::...|
Mouse   211 RSRLATTSFCGSYAGAVIAMPLAGIL-VQYTGWSSVFYVYGSFGMVWYMFWLLVSYESPAKHPTI 274

  Fly   219 SLAERKHIQFALEQNQVIRGATP--PVPWLQILTSRP---FIVLAFCKMSQACSFYTLMQQIPRY 278
            :..||::|:.::.::..:.||..  ..||.:..||.|   .||..||:   :.:||.|:...|.|
Mouse   275 TDEERRYIEESIGESANLLGAMEKFKTPWRKFFTSMPVYAIIVANFCR---SWTFYLLLISQPAY 336

  Fly   279 IHGIFHYSIAANALLSALPFVVM--LMSSYGFIFLAEYLTRRRDISLPILRKTINSFATWTPAVA 341
            ...:|.:.|:...:|||:|.:||  ::...|.|  |::|..::.:|...:||.:|.......|..
Mouse   337 FEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQI--ADFLRSKQILSTTTVRKIMNCGGFGMEATL 399

  Fly   342 LVILSYVSDQNVVGSMFCLIAATAAISGQAI-GSSLNHVDLSPNFAGLLFGMSNTLMSAAGVISP 405
            |:::.|...:.|..|...|   ....||.|| |.::||:|::|.:|.:|.|:||.:.:.:|::.|
Mouse   400 LLVVGYSHTRGVAISFLVL---AVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCP 461

  Fly   406 IVIGLTVTKESDRSQWRTVFLGISVILFLGNLMYLIFGQMTVQSWNDSPSKETETE 461
            |::| .:||...|.:|:.|||..:::.:.|.:.|.:|.....|.|.|  .:||..|
Mouse   462 IIVG-AMTKNKSREEWQYVFLIAALVHYGGVIFYALFASGEKQPWAD--PEETSEE 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3649	NP_611725.2	MFS	23..443	CDD:475125	127/426 (30%)
Slc17a6	NP_543129.3	MFS_SLC17A6_7_8_VGluT	74..498	CDD:340940	127/426 (30%)