DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3649 and slc17a6

DIOPT Version :9

Sequence 1:	NP_611725.2	Gene:	CG3649 / 37626	FlyBaseID:	FBgn0034785	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	XP_004913390.1	Gene:	slc17a6 / 101730310	XenbaseID:	XB-GENE-1011394	Length:	583	Species:	Xenopus tropicalis

Alignment Length:	471	Identity:	140/471 - (29%)
Similarity:	233/471 - (49%)	Gaps:	41/471 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 RFNMSVAIVAFTNANSSNPNYPEYRLTEPQK--------SYTISSPFWGSCCTQMMSGYLSSRFG 92
            |.|:.||||..  .|:|..::....:.|..|        .....|.|||...||:..||::||..
Frog    88 RCNLGVAIVDM--VNNSTIHHGGKIIKEKAKFNWDPEIVGMIHGSFFWGYIVTQIPGGYIASRLA 150

  Fly    93 AKVLLLTIMLLTALLSIATPFALAWGGWQLLFWVRFVQGLAMGGMWPCLYTHLAKWCPKKEANRM 157
            |..:....::||:.|::..|.| |...:..:.:||.:|||..|..:|..:...:||.|..|.:|:
Frog   151 ANRVFGAAIVLTSTLNMLIPSA-ARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRL 214

  Fly   158 GGIMTTGLDCGTIMGFALSGVLSASPLGWPSTFYVPGYLGIVWCLTFLRYGANSPSESKFISLAE 222
            ......|...|.::...|:|:| ....||.|.|||.|..|:||.|.::.....||::...|:..|
Frog   215 ATTSFCGSYAGAVIAMPLAGIL-VQYTGWSSVFYVYGCFGLVWYLFWILVSYESPAKHPTITDEE 278

  Fly   223 RKHIQFALEQNQVIRGATPPV-----PWLQILTSRP---FIVLAFCKMSQACSFYTLMQQIPRYI 279
            |.:|:.::.::..|.|   ||     ||.:..||.|   .||..||:   :.:||.|:...|.|.
Frog   279 RNYIEESIGESANILG---PVEKFKTPWRKFFTSMPVYAIIVANFCR---SWTFYLLLISQPAYF 337

  Fly   280 HGIFHYSIAANALLSALPFVVM--LMSSYGFIFLAEYLTRRRDISLPILRKTINSFATWTPAVAL 342
            ..:|.:.|:...:|||:|.:||  ::...|.|  |::|..::.:|...:||.:|.......|..|
Frog   338 EEVFGFEISKVGMLSAVPHLVMTIIVPIGGQI--ADFLRSKQILSTTTVRKIMNCGGFGMEATLL 400

  Fly   343 VILSYVSDQNVVGSMFCLIAATAAISGQAI-GSSLNHVDLSPNFAGLLFGMSNTLMSAAGVISPI 406
            :::.|...:.|..|...|   ....||.|| |.::||:|::|.:|.:|.|:||.:.:.:|::.|:
Frog   401 LVVGYSHSKGVAISFLVL---AVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPL 462

  Fly   407 VIGLTVTKESDRSQWRTVFLGISVILFLGNLMYLIFGQMTVQSWNDSPSKETETEASPKPQASAP 471
            ::| .:||...|.:|:.|||..:::.:.|.:.|.||.....|.|.| |.:.::.:..   ..:..
Frog   463 IVG-AMTKHKSREEWQYVFLIAALVHYGGVIFYGIFASGEKQPWAD-PEQTSDEKCG---FINED 522

  Fly   472 SVAEET--ISVERFNY 485
            .:|||.  ||....||
Frog   523 ELAEEAGDISQNYINY 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3649	NP_611725.2	MFS	22..442	CDD:119392	127/424 (30%)
CG3649	NP_611725.2	2A0114euk	23..458	CDD:129972	133/440 (30%)
slc17a6	XP_004913390.1	MFS_SLC17A6_7_8_VGluT	74..498	CDD:340940	128/425 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010