Protein Alignment CG3649 and SLC17A4

DIOPT Version :10

• Sequence 1: NP_611725.2
• Gene: CG3649 / 37626
• FlyBaseID: FBgn0034785
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_005486.1
• Gene: SLC17A4 / 10050
• HGNCID: 10932
• Length: 497
• Species: Homo sapiens
• Alignment Length: 473
• Identity: 140/473 - (29%)
• Similarity: 225/473 - (47%)
• Gaps: 58/473 - (12%)

  Fly    17 VRHLQVLFLFLCATLIVAQRFNMSVAIVAFTNANSSNPNYP--------------------EYRL 61
            |||...|.|.||...|..|:.|:|:||.|..| |::.|:.|                    |::.
Human    35 VRHGLALILQLCNFSIYTQQMNLSIAIPAMVN-NTAPPSQPNASTERPSTDSQGYWNETLKEFKA 98

  Fly    62 TEPQKSYT-------ISSPFWGSCCTQMMSGYLSSRFGAKVLLLTIMLLTALLSIATPFALAWGG 119
            ..|...::       :||..:||....:.|||::..||||.::...:.:::.|::..|.| |..|
Human    99 MAPAYDWSPEIQGIILSSLNYGSFLAPIPSGYVAGIFGAKYVVGAGLFISSFLTLFIPLA-ANAG 162

  Fly   120 WQLLFWVRFVQGLAMGGMWPCLYTHLAKWCPKKEANRMGGIMTTGLDCGTIMG---FALSGVLSA 181
            ..||..:|.|||:|...:....|:...||.|..|.::    :||....|:::|   ..|:|.|..
Human   163 VALLIVLRIVQGIAQVMVLTGQYSIWVKWAPPLERSQ----LTTIAGSGSMLGSFIVLLAGGLLC 223

  Fly   182 SPLGWPSTFYVPGYLGIVWCLTFLRYGANSPSESKFISLAERKHIQFALEQNQVIRGATPPVPWL 246
            ..:|||..||:.|.:|...|..:.....:.|....|||..|:::|..:|.|.....|.:.|:  .
Human   224 QTIGWPYVFYIFGGIGCACCPLWFPLIYDDPVNHPFISAGEKRYIVCSLAQQDCSPGWSLPI--R 286

  Fly   247 QILTSRP---FIVLAFCKMSQACSFYTLMQQIPRYIHGIFHYSIAANALLSALPFVVMLMSSYGF 308
            .::.|.|   .:|..||   :...|||:|...|.||..:...::..:.:||||||||      |.
Human   287 AMIKSLPLWAILVSYFC---EYWLFYTIMAYTPTYISSVLQANLRDSGILSALPFVV------GC 342

  Fly   309 I------FLAEYLTRRRDISLPILRKTINSFATWTPAVALVILSYVSDQNVVGSMFCLIAATAAI 367
            |      .||::|..|:.:.|..:||...:.....|:|.||.|.:|...:.: :|..|:.::|..
Human   343 ICIILGGLLADFLLSRKILRLITIRKLFTAIGVLFPSVILVSLPWVRSSHSM-TMTFLVLSSAIS 406

  Fly   368 SGQAIGSSLNHVDLSPNFAGLLFGMSNTLMSAAGVISPIVIGLTVTKESDRSQWRTVFLGISVIL 432
            |....|:.:|.:|::|.:.|.|.|:.......||.|||...|..::::|:.. ||.|||..:.:.
Human   407 SFCESGALVNFLDIAPRYTGFLKGLLQVFAHIAGAISPTAAGFFISQDSEFG-WRNVFLLSAAVN 470

  Fly   433 FLGNLMYLIFGQMTVQSW 450
            ..|.:.|||||:..||.|
Human   471 ISGLVFYLIFGRADVQDW 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3649	NP_611725.2	MFS	23..443	CDD:475125	132/458 (29%)
SLC17A4	NP_005486.1	MFS_SLC17	40..481	CDD:340876	132/459 (29%)