DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3649 and slc17a8

DIOPT Version :9

Sequence 1:	NP_611725.2	Gene:	CG3649 / 37626	FlyBaseID:	FBgn0034785	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	XP_002936892.1	Gene:	slc17a8 / 100489470	XenbaseID:	XB-GENE-988965	Length:	588	Species:	Xenopus tropicalis

Alignment Length:	474	Identity:	136/474 - (28%)
Similarity:	233/474 - (49%)	Gaps:	41/474 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 RFNMSVAIVAFTNANS----SNPNYPEYRLT-EPQKSYTI-SSPFWGSCCTQMMSGYLSSRFGAK 94
            |.|:.||||...|.|:    ..|...:.:.. :|:....| .|.|||...||:..|:::::..|.
Frog    93 RCNLGVAIVEMVNNNTVYVDGKPEMQKAQFNWDPETVGLIHGSFFWGYIITQIPGGFIANKLAAN 157

  Fly    95 VLLLTIMLLTALLSIATPFALAWGGWQLLFWVRFVQGLAMGGMWPCLYTHLAKWCPKKEANRMGG 159
            .:....:.||::|::..|.| |...:..:..||.:|||..|..:|..:...:||.|..|.:|:..
Frog   158 RVFGAAIFLTSILNMLIPSA-ARVHFGCVISVRVLQGLVEGVTYPACHGMWSKWAPPLERSRLAT 221

  Fly   160 IMTTGLDCGTIMGFALSGVLSASPLGWPSTFYVPGYLGIVWCLTFLRYGANSPSESKFISLAERK 224
            ....|...|.::...|:||| ...:||||.||:.|..|:.|.:.:|.:...||:....|:..||.
Frog   222 TSFCGSYAGAVIAMPLAGVL-VQYIGWPSVFYIYGVFGMCWYVFWLLHATESPAAHPSITFEERT 285

  Fly   225 HIQFAL-EQNQVIRGATPPVPWLQILTSRP---FIVLAFCKMSQACSFYTLMQQIPRYIHGIFHY 285
            :|:.:: |.:.::.......||.:..||.|   .||..||:   :.:||.|:...|.|...:|.:
Frog   286 YIETSIGEGSNLVTTGKFKTPWKKFFTSMPVYAIIVANFCR---SWTFYLLLISQPAYFEEVFGF 347

  Fly   286 SIAANALLSALPFVVMLMSSYGFIFLAEYLTRRRDISLPILRKTINSFATWTPAVALVILSYVSD 350
            .|:...||||:|.:||.:.......||::|..|:.:|...:||.:|.......|..|:::.| |.
Frog   348 PISKVGLLSAVPHMVMTIIVPVGGQLADFLRSRKILSTTTVRKIMNCGGFGMEATLLLVVGY-SH 411

  Fly   351 QNVVGSMFCLIAATAAISGQAI-GSSLNHVDLSPNFAGLLFGMSNTLMSAAGVISPIVIGLTVTK 414
            ...:...|.::|  ...||.|| |.::||:|::|.:|.:|.|:||.:.:.:|::.|:::| .:||
Frog   412 TKAISISFLVLA--VGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVG-AMTK 473

  Fly   415 ESDRSQWRTVFLGISVILFLGNLMYLIFGQMTVQSW---------------NDSPSKETE----- 459
            ...|.:|:.|||..:::.:.|.:.|.||.....|.|               ||..::|||
Frog   474 NKTREEWQNVFLIAAIVHYSGVIFYGIFASGEKQEWADPESLSEDKCGIIDNDELAEETELNNES 538

  Fly   460 -TEASPKPQASAPSVAEET 477
             |.::.|....:...:.||
Frog   539 FTSSNKKSSYGSTIHSNET 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3649	NP_611725.2	MFS	22..442	CDD:119392	123/416 (30%)
CG3649	NP_611725.2	2A0114euk	23..458	CDD:129972	129/447 (29%)
slc17a8	XP_002936892.1	2A0114euk	75..513	CDD:129972	127/428 (30%)
slc17a8	XP_002936892.1	MFS	81..502	CDD:119392	124/417 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010