DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3649 and slc17a7b

DIOPT Version :9

Sequence 1:	NP_611725.2	Gene:	CG3649 / 37626	FlyBaseID:	FBgn0034785	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	XP_009295917.2	Gene:	slc17a7b / 100331980	ZFINID:	ZDB-GENE-131125-32	Length:	585	Species:	Danio rerio

Alignment Length:	470	Identity:	137/470 - (29%)
Similarity:	228/470 - (48%)	Gaps:	47/470 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 RFNMSVAIVAFTNANSSNPNYPEYR-----LTEPQKSY---TI----SSPFWGSCCTQMMSGYLS 88
            |.|:.||:|:..|      |:..||     :.:.|.|:   |:    .|.|||...||:..|::.
Zfish    80 RCNLGVAVVSMVN------NHTVYRDGKPYIVKAQFSWDPETVGMIHGSFFWGYIVTQIPGGFIC 138

  Fly    89 SRFGAKVLLLTIMLLTALLSIATPFA--LAWGGWQLLFWVRFVQGLAMGGMWPCLYTHLAKWCPK 151
            .:|.|..:....::.|::|::..|.|  :.:|   .:..||.:|||..|..:|..:...|||.|.
Zfish   139 QKFAANRVFGFAVVSTSILNMMIPTAARMHFG---CVILVRILQGLVEGVSYPACHGIWAKWAPP 200

  Fly   152 KEANRMGGIMTTGLDCGTIMGFALSGVLSASPLGWPSTFYVPGYLGIVWCLTFLRYGANSPSESK 216
            .|.:|:......|...|.::...|:||| ....||.|.|||.|..|:.|.|.::.....||:...
Zfish   201 LERSRLATTAFCGSYAGAVIAMPLAGVL-VQYSGWSSVFYVYGSFGVCWYLFWILVSYESPAAHP 264

  Fly   217 FISLAERKHIQFALEQNQVIRGATPPV-----PWLQILTSRP---FIVLAFCKMSQACSFYTLMQ 273
            .|:..|||:|:.|:.::   .|...|:     ||.|..||.|   .||..||:   :.:||.|:.
Zfish   265 TITPEERKYIEDAIGES---AGLVNPLTKFNTPWRQFFTSMPVYAIIVANFCR---SWTFYLLLI 323

  Fly   274 QIPRYIHGIFHYSIAANALLSALPFVVMLMSSYGFIFLAEYLTRRRDISLPILRKTINSFATWTP 338
            ..|.|...:|.:.|:...:|||||.:||.:.......||:||.....::...:||.:|.......
Zfish   324 SQPAYFEEVFKFEISKVGILSALPHLVMTIVVPIGGQLADYLRTHNLMTTTNVRKLMNCGGFGLE 388

  Fly   339 AVALVILSYVSDQNVVGSMFCLIAATAAISGQAI-GSSLNHVDLSPNFAGLLFGMSNTLMSAAGV 402
            |..|:::.:...:.|..|...|   ....||.|| |.::||:|::|.:|.:|.|:||.:.:.:|:
Zfish   389 ATFLLVVGFSHTKGVAISFLVL---AVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGM 450

  Fly   403 ISPIVIGLTVTKESDRSQWRTVFLGISVILFLGNLMYLIFGQMTVQSWNDSPSKETETEASPKPQ 467
            :.|:::| .:||...|.:|:.|||..|::.:.|.:.|.:|.....|.|.: |...:|.:..   .
Zfish   451 VCPLIVG-AMTKNKTREEWQYVFLIASLVHYGGVIFYGLFASGEKQPWAE-PENTSEEKCG---I 510

  Fly   468 ASAPSVAEETISVER 482
            .....:|:||..:.|
Zfish   511 LGEDELADETEELYR 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3649	NP_611725.2	MFS	22..442	CDD:119392	128/428 (30%)
CG3649	NP_611725.2	2A0114euk	23..458	CDD:129972	132/444 (30%)
slc17a7b	XP_009295917.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582495
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.750