DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9826 and VHT1

DIOPT Version :9

Sequence 1:	NP_611724.1	Gene:	CG9826 / 37625	FlyBaseID:	FBgn0034784	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_011579.1	Gene:	VHT1 / 852956	SGDID:	S000003297	Length:	593	Species:	Saccharomyces cerevisiae

Alignment Length:	492	Identity:	103/492 - (20%)
Similarity:	170/492 - (34%)	Gaps:	129/492 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 SVAIVAMTNAATTNPNFPEFEWTEKQKSYILSSFY--WGYILTLFPGSFLCRRYGAKVVLFVASC 98
            ||.:...|||..:|   .:.:...|...|:.:|..  .|.|:...|..:|..|:.:.::|.|...
Yeast   141 SVDLNNYTNAYVSN---MKEDLNMKGNDYVYTSTIANVGAIVFQLPFMYLLPRFPSHIILPVMDL 202

  Fly    99 GTAVLSLMTPWCITWGGWQVFC----------AIRILQGLFQGVIFPCVTEHLAMWSPPEERNRL 153
            |         |  ||  :...|          |.|.:...|....:|.....|..|..|:|.|..
Yeast   203 G---------W--TW--FTFACYRANSLAELRAYRFILSAFGAAYYPVSQYILGCWYAPDEINSR 254

  Fly   154 GAFSYTGTDCGTVLAMFISGMIAKGAMGWPGISYVSGSLCAAWCFLWLIFASNNATESRFVG--- 215
            ....:.|...|:|.:..:...|.|...|..|:        |.|.:::||.|...:..:..:|
Yeast   255 VCLFFCGQQLGSVTSGLLQSRIFKSLNGVHGL--------AGWRWMFLIDAIAISLPTAIIGFFV 311

  Fly   216 --------------EAECKYIESSLEHNEDFHG----RTIPIPWRAIWTSV---PFLALLVTRCA 259
                          :.|.:...:..:.|:...|    :..|:..|.:|..|   |...:||.  .
Yeast   312 IPGVPSKCYSLFLTDEEIRIARARNKRNQIKDGVDKSKLAPLWSRKLWKKVFCTPAFWVLVV--F 374

  Fly   260 ETYGLSTLQAEIPSYMNGVLNMEIQSNAVFS-----SLPFLAMWLLSYVYLI----AADVLLKKK 315
            :|...:.:.|...||     .:.::||..:|     :|..:.. .|.:.|:|    .||:...|.
Yeast   375 DTCSWNNMTAYSGSY-----TLWLKSNTKYSIAQVNNLSVIPA-CLGFAYVIFCAFGADLFRCKW 433

  Fly   316 ILSLTAVRKLFNTLSFWIPAAALIGIGFLSEENKNLAIVLMTVSVGVNSGATIGSSLNS-IDLSP 379
            |..:.|.  :.||:|    .|.||.....|   |.......|....|.:...:.|.:|. :...|
Yeast   434 IFMVFAA--IMNTVS----CALLIKWDIPS---KAKWYAFFTTYFSVAASPCLWSFINDFLRFDP 489

  Fly   380 NHAGI----LIGLSNTVANVIPIL---------------TPLIAGEIVADKHNRGQWQIVFGLAA 425
            ....|    :...|.:....||.|               ..||.|.|.      |.|..|
Yeast   490 QVKAITWIAIYSFSQSTYAWIPTLAWPTVESPRFKTGYTVSLIFGAIY------GLWTFV----- 543

  Fly   426 VIFF---------VGNVVFIIWGTAKAQPWDADDFLK 453
            |:||         :||.: |::.:.|.:  :..:|:|
Yeast   544 VLFFYKRNEKKHALGNGI-ILYDSNKGE--ELPEFVK 577

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9826	NP_611724.1	2A0114euk	14..450	CDD:129972	101/487 (21%)
CG9826	NP_611724.1	MFS	19..438	CDD:119392	100/475 (21%)
VHT1	NP_011579.1	MFS_FEN2_like	124..542	CDD:340885	93/447 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I2980
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000