DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9826 and Slc17a6

DIOPT Version :9

Sequence 1:	NP_611724.1	Gene:	CG9826 / 37625	FlyBaseID:	FBgn0034784	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_445879.1	Gene:	Slc17a6 / 84487	RGDID:	620531	Length:	582	Species:	Rattus norvegicus

Alignment Length:	473	Identity:	145/473 - (30%)
Similarity:	243/473 - (51%)	Gaps:	37/473 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CKG-PRLGVRHLQSFLLFLGLTVMHIARLNVSVAIVAMTNAATTN------PNFPEFEWTEKQKS 63
            |.| ||   |::.:.:..||..:....|.|:.||||.|.|.:|.:      ....:|.|..:...
  Rat    64 CFGLPR---RYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNWDPETVG 125

  Fly    64 YILSSFYWGYILTLFPGSFLCRRYGAKVVLFVASCGTAVLSLMTP-------WCITWGGWQVFCA 121
            .|..||:||||:|..||.::..|..|..|...|...|:.|:::.|       .|:.:
  Rat   126 MIHGSFFWGYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYGCVIF-------- 182

  Fly   122 IRILQGLFQGVIFPCVTEHLAMWSPPEERNRLGAFSYTGTDCGTVLAMFISGMIAKGAMGWPGIS 186
            :||||||.:||.:|......:.|:||.||:||...|:.|:..|.|:||.::|::.: ..||..:.
  Rat   183 VRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQ-YTGWSSVF 246

  Fly   187 YVSGSLCAAWCFLWLIFASNNATESRFVGEAECKYIESSLEHNEDFHG--RTIPIPWRAIWTSVP 249
            ||.||....|...||:.:..:..:...:.:.|.:|||.|:..:.:..|  .....|||..:||:|
  Rat   247 YVYGSFGMVWYMFWLLVSYESPAKHPTITDEERRYIEESIGESANLLGAMEKFKTPWRKFFTSMP 311

  Fly   250 FLALLVTRCAETYGLSTLQAEIPSYMNGVLNMEIQSNAVFSSLPFLAMWLLSYVYLIAADVLLKK 314
            ..|::|.....::....|....|:|...|...||....:.|::|.|.|.::..:....||.|..|
  Rat   312 VYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSK 376

  Fly   315 KILSLTAVRKLFNTLSFWIPAAALIGIGFLSEENKNLAIVLMTVSVGVNSGATIGSSLNSIDLSP 379
            :|||.|.|||:.|...|.:.|..|:.:|:  ...:.:||..:.::||.:..|..|.::|.:|::|
  Rat   377 QILSTTTVRKIMNCGGFGMEATLLLVVGY--SHTRGVAISFLVLAVGFSGFAISGFNVNHLDIAP 439

  Fly   380 NHAGILIGLSNTVANVIPILTPLIAGEIVADKHNRGQWQIVFGLAAVIFFVGNVVFIIWGTAKAQ 444
            .:|.||:|:||.|..:..::.|:|.|.:..:| :|.:||.||.:||::.:.|.:.:.::.:.:.|
  Rat   440 RYASILMGISNGVGTLSGMVCPIIVGAMTKNK-SREEWQYVFLIAALVHYGGVIFYALFASGEKQ 503

  Fly   445 PWDADDFLKPKDT-ESAC 461
            || ||    |::| |..|
  Rat   504 PW-AD----PEETSEEKC 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9826	NP_611724.1	2A0114euk	14..450	CDD:129972	136/450 (30%)
CG9826	NP_611724.1	MFS	19..438	CDD:119392	131/433 (30%)
Slc17a6	NP_445879.1	2A0114euk	70..511	CDD:129972	138/457 (30%)
Slc17a6	NP_445879.1	MFS	75..498	CDD:119392	131/434 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	47	1.000	Domainoid score	I11657
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910