DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9826 and slc17a5

DIOPT Version :9

Sequence 1:	NP_611724.1	Gene:	CG9826 / 37625	FlyBaseID:	FBgn0034784	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_001070195.1	Gene:	slc17a5 / 767760	ZFINID:	ZDB-GENE-060929-1158	Length:	488	Species:	Danio rerio

Alignment Length:	465	Identity:	160/465 - (34%)
Similarity:	259/465 - (55%)	Gaps:	40/465 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CKGPRLGVRHLQSFLLFLGLTVMHIARLNVSVAIVAM--------TNAATTNP-NFP-------- 53
            |...|.|:    :||...|..|.:..|:|:|||:|.|        |:::...| |.|
Zfish    32 CGSSRYGL----AFLSCYGFFVAYALRVNLSVAMVDMLKNSSKANTSSSICPPHNIPVPKHNHTA 92

  Fly    54 -EFEWTEKQKSYILSSFYWGYILTLFPGSFLCRRYGAKVVLFVASCGTAVLSLMTPWCITWG-GW 116
             .::|..:.:.:||.||::|||:|..||.:|.|:||||.:|.:....|.:.:|:||.....| |:
Zfish    93 MVYDWNSETQGWILGSFFYGYIITQIPGGYLARKYGAKWLLGLGILCTVIFTLLTPLAADLGAGY 157

  Fly   117 QVFCAIRILQGLFQGVIFPCVTEHLAMWSPPEERNRLGAFSYTGTDCGTVLAMFISGMIAKGAMG 181
            .:  |:|:|:|:.:||.:|.:....|.|:||.||:||...||||...|||:|:.:||.|. ..:.
Zfish   158 LI--AVRVLEGIGEGVTYPAMHAMWASWAPPLERSRLLTISYTGAQLGTVVALPLSGQIC-FYLD 219

  Fly   182 WPGISYVSGSLCAAWCFLWLIFASNNATESRFVGEAECKYIESSLEH----NEDFHGRTIPIPWR 242
            |..:.|:.|::...|.|||:.|.||:.:..:.:.|||..||.|||::    .:|:      |||.
Zfish   220 WTYVFYIFGAVGLLWFFLWICFVSNSPSSHKRITEAEKTYIMSSLKNELSPTQDY------IPWT 278

  Fly   243 AIWTSVPFLALLVTRCAETYGLSTLQAEIPSYMNGVLNMEIQSNAVFSSLPFLAMWLLSYVYLIA 307
            :|:.|:|..|::|...:..:...||...:|:|||.||...||.|.:.|:||:|..|||:.:....
Zfish   279 SIFKSMPLWAIVVAHFSYNWTFYTLLTLLPTYMNDVLGFSIQQNGMLSALPYLGCWLLALLGGQL 343

  Fly   308 ADVLLKKKILSLTAVRKLFNTLSFWIPAAALIGIGFLSEENKNLAIVLMTVSVGVNSGATIGSSL 372
            ||:|.::.:.....|||.|..:....||..|:..|: :..|..||:..:|:|..:...:..|.::
Zfish   344 ADLLRERFLFRTVIVRKAFTVVGMAGPAVFLVAAGY-TGCNYILAVAFLTISSSLGGISASGFNI 407

  Fly   373 NSIDLSPNHAGILIGLSNTVANVIPILTPLIAGEIVADKHNR-GQWQIVFGLAAVIFFVGNVVFI 436
            |.:|::|::||||:|::|:.|.:..::.|:||..:.  |.|. .:|||||.::|.|...|.|.|.
Zfish   408 NHLDIAPSYAGILLGITNSFATIPGMVGPVIARSLT--KSNTIPEWQIVFYISAAINIFGAVFFT 470

  Fly   437 IWGTAKAQPW 446
            |:|....|||
Zfish   471 IFGKGTVQPW 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9826	NP_611724.1	2A0114euk	14..450	CDD:129972	157/457 (34%)
CG9826	NP_611724.1	MFS	19..438	CDD:119392	152/442 (34%)
slc17a5	NP_001070195.1	2A0114euk	27..488	CDD:129972	160/465 (34%)
slc17a5	NP_001070195.1	MFS	92..472	CDD:119392	137/391 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582559
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D619250at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.950