DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9826 and slc17a8

DIOPT Version :9

Sequence 1:	NP_611724.1	Gene:	CG9826 / 37625	FlyBaseID:	FBgn0034784	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_001076304.1	Gene:	slc17a8 / 563467	ZFINID:	ZDB-GENE-060503-416	Length:	590	Species:	Danio rerio

Alignment Length:	488	Identity:	151/488 - (30%)
Similarity:	243/488 - (49%)	Gaps:	37/488 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CKGPRLGVRHLQSFLLFLGLTVMHIARLNVSVAIVAMTNAATTNPNF------PEFEWTEKQKSY 64
            |.|  |..|::.:.|..||..:....|.|:.||||.|.|..|...|.      .:|.|..:....
Zfish    69 CFG--LPKRYIIAMLSGLGFCISFGIRCNLGVAIVEMVNNNTVYINGTAVMQPAQFNWDPETVGL 131

  Fly    65 ILSSFYWGYILTLFPGSFLCRRYGAKVVLFVASCGTAVLSLMTP-------WCITWGGWQVFCAI 122
            |..||:||||:|..||.|:..:..|..|...|...|:||::..|       .|:.:        :
Zfish   132 IHGSFFWGYIVTQIPGGFISNKLAANRVFGAAIFLTSVLNMFIPSAARVHYGCVMF--------V 188

  Fly   123 RILQGLFQGVIFPCVTEHLAMWSPPEERNRLGAFSYTGTDCGTVLAMFISGMIAKGAMGWPGISY 187
            ||||||.:||.:|......:.|:||.||:||...|:.|:..|.|:||.::|::.: .:|||.:.|
Zfish   189 RILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQ-YVGWPSVFY 252

  Fly   188 VSGSLCAAWCFLWLIFASNNATESRFVGEAECKYIESSLEHNEDFHGRT--IPIPWRAIWTSVPF 250
            :.|.....|...|::.|.|:......:.|.|..|||:|:....:....|  ...|||..:||:|.
Zfish   253 IYGVFGIIWYIFWILLAYNSPAVHPTISEEERNYIETSIGEGANLMSSTEKFKTPWREFFTSMPV 317

  Fly   251 LALLVTRCAETYGLSTLQAEIPSYMNGVLNMEIQSNAVFSSLPFLAMWLLSYVYLIAADVLLKKK 315
            .|::|.....::....|....|:|...|....|....:.|::|.:.|.::..:....||.|..:|
Zfish   318 YAIIVANFCRSWTFYLLLISQPAYFEEVFGFPISKVGILSAVPHMVMTIIVPIGGQLADFLRSRK 382

  Fly   316 ILSLTAVRKLFNTLSFWIPAAALIGIGFLSEENKNLAIVLMTVSVGVNSGATIGSSLNSIDLSPN 380
            |||.|.|||:.|...|.:.|..|:.:||  ...:.:||..:.::||.:..|..|.::|.:|::|.
Zfish   383 ILSTTTVRKIMNCGGFGMEATLLLVVGF--SHTRAVAISFLILAVGFSGFAISGFNVNHLDIAPR 445

  Fly   381 HAGILIGLSNTVANVIPILTPLIAGEIVADKHNRGQWQIVFGLAAVIFFVGNVVFIIWGTAKAQP 445
            :|.||:|:||.|..:..::.|||.|.:...| .|.:||.||.:|:::.:.|.:.:.|:.:.:.|.
Zfish   446 YASILMGISNGVGTLSGMVCPLIVGALTKHK-TRLEWQHVFVIASMVHYTGVIFYAIFASGEKQD 509

  Fly   446 WDADDFLKPKDTESACEKPKIT-PAEVAPPIDP 477
            | ||    |::|..  ||..|. ..|:|...:|
Zfish   510 W-AD----PENTSD--EKCGIIGEDELADETEP 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9826	NP_611724.1	2A0114euk	14..450	CDD:129972	139/450 (31%)
CG9826	NP_611724.1	MFS	19..438	CDD:119392	134/433 (31%)
slc17a8	NP_001076304.1	2A0114euk	75..514	CDD:129972	140/455 (31%)
		MFS	81..503	CDD:119392	135/433 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	526..590		3/10 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582529
Domainoid	1	1.000	42	1.000	Domainoid score	I12425
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.840