DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9826 and MFS14

DIOPT Version :9

Sequence 1:	NP_611724.1	Gene:	CG9826 / 37625	FlyBaseID:	FBgn0034784	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_001286591.1	Gene:	MFS14 / 46085	FlyBaseID:	FBgn0010651	Length:	497	Species:	Drosophila melanogaster

Alignment Length:	490	Identity:	180/490 - (36%)
Similarity:	291/490 - (59%)	Gaps:	42/490 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 GVRHLQSFLLFLGLTVMHIARLNVSVAIVAMTNAAT------TN----PNFPEFE---------W 57
            ||||:|..|.|..|.:.:..|:|:|||:||||:.:|      ||    |:.|.|:         :
  Fly    21 GVRHVQCILCFFCLAMSYAWRVNLSVALVAMTDNSTSLAQNNTNTGVAPSEPGFDFFNSERYYNF 85

  Fly    58 TEKQKSYILSSFYWGYILTLFPGSFLCRRYGAKVVLFVASCGTAVLSLMTPWCITWGGWQVFCAI 122
            |:|:|..:.:||::|||:|..||.::.:|||||.:|.......|::::::|..:.: ||.....:
  Fly    86 TQKEKGNLQASFFFGYIVTQVPGGYIAQRYGAKTMLMYGLGIAALITMLSPMSLQF-GWVALAVM 149

  Fly   123 RILQGLFQGVIFPCVTEHLAMWSPPEERNRLGAFSYTGTDCGTVLAMFISGMIAKGAMGWPGISY 187
            |.:.||.||.:.|.....||.|||.:||..||...|:|...|||:.:..||.||...:|||.|.|
  Fly   150 RFVMGLAQGAVHPATHALLAKWSPADERGMLGTLCYSGAQFGTVVMLATSGFIADSVLGWPSIFY 214

  Fly   188 VSGSLCAAWCFLWLIFASNNATESRFVGEAECKYIESS-----LEHNEDFHGRTIPIPWRAIWTS 247
            :.|:....|...|.:|:::...|.|.:...|.|||..|     ::..|    :..|.||:||::|
  Fly   215 LGGACGFIWMVFWYLFSASTPEEHRLISPGELKYITDSRSDGKMQSAE----KLAPTPWKAIFSS 275

  Fly   248 VPFLALLVTRCAETYGLSTLQAEIPSYMNGVLNMEIQSNAVFSSLPFLAMWLLSYVYLIAADVLL 312
            :|||:|||..|...:|...|..:||:||..:.:::|:..|:.||||::.|.|||:.::..:.||.
  Fly   276 LPFLSLLVVHCTHIFGYWLLLMQIPTYMKKIYHVDIKKGALLSSLPYMVMLLLSFFFVWLSKVLQ 340

  Fly   313 KKKILSLTAVRKLFNTLSFWIPAAALIGIGFLSEENKNLAIVLMTVSVGVNSGATIGSSLNSIDL 377
            ||:.:||:..||:||::..|||..:||.:|::..:|..||:.|:|::||::....:|..:|.|||
  Fly   341 KKEGMSLSFNRKIFNSIGHWIPMLSLIALGYVPADNAPLAVTLLTLTVGISGATYLGFQVNHIDL 405

  Fly   378 SPNHAGILIGLSNTVANVIPILTPLIAGEIVADKHNRGQWQIVFGLAAVIFFVGNVVFIIWGTAK 442
            |||:||.|:|::|..|||:..:.|:|.|:||.|:.:..:|::||.|||..:|:||::|:|:|..:
  Fly   406 SPNYAGTLMGITNCAANVMSGIAPVIVGQIVVDETSVTEWRLVFLLAAAFYFLGNLLFVIFGRTE 470

  Fly   443 AQPWDADDFLKPKDTESACEKPKITPAEVAPPIDP 477
            .|.||:     |:|.:.        .||...|:.|
  Fly   471 VQWWDS-----PRDNKE--------DAEQGTPLAP 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9826	NP_611724.1	2A0114euk	14..450	CDD:129972	172/459 (37%)
CG9826	NP_611724.1	MFS	19..438	CDD:119392	164/442 (37%)
MFS14	NP_001286591.1	2A0114euk	19..477	CDD:129972	174/465 (37%)
MFS14	NP_001286591.1	MFS	81..466	CDD:119392	146/389 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442709
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D428976at33208
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	9.000