DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9826 and MFS10

DIOPT Version :9

Sequence 1:	NP_611724.1	Gene:	CG9826 / 37625	FlyBaseID:	FBgn0034784	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_001285188.1	Gene:	MFS10 / 32263	FlyBaseID:	FBgn0030452	Length:	559	Species:	Drosophila melanogaster

Alignment Length:	490	Identity:	160/490 - (32%)
Similarity:	256/490 - (52%)	Gaps:	59/490 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 GPRLGVRHLQSFLLFLGLTVMHIARLNVSVAIVAMTNAAT-----------------------TN 49
            ||:  .||:..|:.|||..|::..|:|:|||||||.|...                       ::
  Fly    64 GPK--TRHIFGFMGFLGFAVVYAMRVNLSVAIVAMVNQTAIPHSNSSVIDTDTCPLPAPHHNGSD 126

  Fly    50 PNFP----EFEWTEKQKSYILSSFYWGYILTLFPGSFLCRRYGAKVVLFVASCGTAVLSLMTPWC 110
            || |    ||.|.|..:..:|.||::||:||..||..:...||.|.:.......|||.:|:||..
  Fly   127 PN-PQKEGEFVWDEATQGLVLGSFFYGYVLTQVPGGRMAELYGGKKIYGYGVLITAVFTLITPLA 190

  Fly   111 ITWGGWQVFCAIRILQGLFQGVIFPCVTEHLAMWSPPEERNRLGAFSYTGTDCGTVLAMFISGMI 175
            ..| ...:...:|||:|:.:||.:|.:...||.|.||.|||:..|..|.|::.|||::|.::|.:
  Fly   191 AHW-DLPLLVLVRILEGMGEGVTYPAMHAMLAHWIPPLERNKFAAIVYAGSNIGTVISMPLAGWL 254

  Fly   176 AK----GAMGWPGISYVSGSLCAAWCFLWLIFASNNATESRFVGEAECKYIESSLE--------- 227
            ..    |  |||...|:.|.|...|...|:....:..::...:.|:|.:|||.||:
  Fly   255 CSLDFLG--GWPSAFYIFGLLGILWFIAWMYLVYDKPSDHPRISESEREYIERSLQVQRLINQDL 317

  Fly   228 -HNEDFHGR---------TIPIPWRAIWTSVPFLALLVTRCAETYGLSTLQAEIPSYMNGVLNME 282
             ..|:..|:         ..||||.::.||||..|:|:|:|.:.:...|...|:|:||:.:|:.:
  Fly   318 AEAEEEEGQDEVSLRAPPEEPIPWSSLLTSVPLWAILLTQCGQGWAFYTQLTELPTYMSNILHFD 382

  Fly   283 IQSNAVFSSLPFLAMWLLSYVYLIAADVLLKKKILSLTAVRKLFNTLSFWIPAAALIGIGFLSEE 347
            |||||:.:::|:|..|.:.......||.:|.::.:||....||:||::..:|:..||||.::..:
  Fly   383 IQSNALLNAVPYLTSWFVGIACSALADWMLARRYISLLNSYKLWNTVASVVPSLGLIGIIYVGCD 447

  Fly   348 NKNLAIVLMTVSVGVNSGAT-IGSSLNSIDLSPNHAGILIGLSNTVANVIPILTPLIAGEIVADK 411
              .:.:..|...||...||. .|:.:|.|.|||.:||.:.|::|:.||:...|.|.:.|.|:..:
  Fly   448 --WVWVTFMLAGVGSFGGAVYAGNQMNHIALSPRYAGTMYGITNSAANICGFLAPYVIGLIINHR 510

  Fly   412 HNRGQWQIVFGLAAVIFFVGNVVFIIWGTAKAQPW 446
            ....||.:||.|||.:...||.:::|:.:|:.|.|
  Fly   511 ETLTQWHLVFWLAAGLNIAGNFIYLIFASAEEQSW 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9826	NP_611724.1	2A0114euk	14..450	CDD:129972	158/484 (33%)
CG9826	NP_611724.1	MFS	19..438	CDD:119392	152/469 (32%)
MFS10	NP_001285188.1	2A0114euk	63..547	CDD:129972	160/490 (33%)
MFS10	NP_001285188.1	MFS	134..538	CDD:119392	135/408 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	7	7.060