DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9826 and Slc17a4

DIOPT Version :9

Sequence 1:	NP_611724.1	Gene:	CG9826 / 37625	FlyBaseID:	FBgn0034784	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_795990.2	Gene:	Slc17a4 / 319848	MGIID:	2442850	Length:	492	Species:	Mus musculus

Alignment Length:	461	Identity:	134/461 - (29%)
Similarity:	235/461 - (50%)	Gaps:	36/461 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 VRHLQSFLLFLGLTVMHIARLNVSVAIVAMT---------NAATTNP---------------NFP 53
            :||..:|:|.|....::..::|:|.||.||.         ||:|..|               ..|
Mouse    32 LRHGLAFILHLCNFSIYTQQMNLSFAITAMVNTTVASSQLNASTERPPTNSQDVWNETLQESKAP 96

  Fly    54 EFEWTEKQKSYILSSFYWGYILTLFPGSFLCRRYGAKVVLFVASCGTAVLSLMTPWCITWGGWQV 118
            .::||.:.:..:|||..:|..:...|..::...:|||.|:.:....::||:|..|.... .|..:
Mouse    97 VYDWTPEIQGILLSSLSYGSFIAPIPTGYVAGVFGAKYVVGLGLLISSVLTLFIPLAAD-AGVAL 160

  Fly   119 FCAIRILQGLFQGVIFPCVTEHLAMWSPPEERNRLGAFSYTGTDCGTVLAMFISGMIAKGAMGWP 183
            ...:|::||:.|.::........|.|:||:||::|...:.:|:..||.|.:...|:|.: |:|||
Mouse   161 LIVLRVIQGMAQVMVLTGQYSLWAKWAPPQERSQLITIAASGSMLGTFLVLIAGGLICQ-ALGWP 224

  Fly   184 GISYVSGSLCAAWCFLWLIFASNNATESRFVGEAECKYIESSLEHNEDFHGRTIPIPWRAIWTSV 248
            .|.|:.|.:..|.|.||.....::.....|:...|.:||..||...:...|.::||  :|:..|:
Mouse   225 YIFYIFGGIGCACCLLWFPLVYDDPQNHPFISTGERRYITCSLAQEDCSLGWSLPI--KAMVKSL 287

  Fly   249 PFLALLVTRCAETYGLSTLQAEIPSYMNGVLNMEIQSNAVFSSLPFLAMWLLSYVYLIAADVLLK 313
            |..|::|:...|.:.|||:.|..|:|::.||...::.:.:.|:|||:...:...:..:.||.||.
Mouse   288 PLWAIVVSYFCEYWLLSTVMAYTPTYISSVLQANLRDSGILSALPFMFGCVCIILGGLLADFLLS 352

  Fly   314 KKILSLTAVRKLFNTLSFWIPAAALIGIGFL-SEENKNLA-IVLMTVSVGV-NSGATIGSSLNSI 375
            :|||.|..:||||..:.....:..|:.:.:: |..:..:| :||.:|...: :|||.|    |.:
Mouse   353 RKILRLVTIRKLFTAVGVLASSGILLPLPWVRSSRSTTMAFLVLSSVFASLCDSGALI----NFL 413

  Fly   376 DLSPNHAGILIGLSNTVANVIPILTPLIAGEIVADKHNRGQWQIVFGLAAVIFFVGNVVFIIWGT 440
            |::|.:||.|.||....:.:...:.|.:||..::.....| |:.||.|||.|..||.:.::|:..
Mouse   414 DIAPRYAGFLKGLLQVFSYLAGGIAPTVAGFFISQDSEFG-WRNVFFLAAAIDVVGLLFYLIFSR 477

  Fly   441 AKAQPW 446
            |:.|.|
Mouse   478 AEVQDW 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9826	NP_611724.1	2A0114euk	14..450	CDD:129972	134/460 (29%)
CG9826	NP_611724.1	MFS	19..438	CDD:119392	128/445 (29%)
Slc17a4	NP_795990.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		2A0114euk	27..486	CDD:129972	134/461 (29%)
		MFS	98..475	CDD:119392	114/385 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838718
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840