DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9826 and SLC17A5

DIOPT Version :9

Sequence 1:	NP_611724.1	Gene:	CG9826 / 37625	FlyBaseID:	FBgn0034784	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_001369562.1	Gene:	SLC17A5 / 26503	HGNCID:	10933	Length:	533	Species:	Homo sapiens

Alignment Length:	427	Identity:	134/427 - (31%)
Similarity:	224/427 - (52%)	Gaps:	31/427 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 RHLQSFLLFLGLTVMHIARLNVSVAIVAMTNAATT---------------------NPNFPEFEW 57
            |:..:.|.|.|..:::..|:|:|||:|.|.::.||                     |....:::|
Human    39 RYNLAILAFFGFFIVYALRVNLSVALVDMVDSNTTLEDNRTSKACPEHSAPIKVHHNQTGKKYQW 103

  Fly    58 TEKQKSYILSSFYWGYILTLFPGSFLCRRYGAKVVLFVASCGTAVLSLMTPWCITWGGWQVFCAI 122
            ..:.:.:||.||::|||:|..||.::..:.|.|::|.....|||||:|.||.....|...:. .:
Human   104 DAETQGWILGSFFYGYIITQIPGGYVASKIGGKMLLGFGILGTAVLTLFTPIAADLGVGPLI-VL 167

  Fly   123 RILQGLFQGVIFPCVTEHLAMWSPPEERNRLGAFSYTGTDCGTVLAMFISGMIAKGAMGWPGISY 187
            |.|:||.:||.||.:....:.|:||.||::|.:.||.|...|||:::.:||:|.. .|.|..:.|
Human   168 RALEGLGEGVTFPAMHAMWSSWAPPLERSKLLSISYAGAQLGTVISLPLSGIICY-YMNWTYVFY 231

  Fly   188 VSGSLCAAWCFLWLIFASNNATESRFVGEAECKYIESSLEHNEDFHGRTIPIPWRAIWTSVPFLA 252
            ..|::...|..||:...|:...:.:.:...|.:||.|||.:......   .:||..|..|:|..|
Human   232 FFGTIGIFWFLLWIWLVSDTPQKHKRISHYEKEYILSSLRNQLSSQK---SVPWVPILKSLPLWA 293

  Fly   253 LLVTRCAETYGLSTLQAEIPSYMNGVLNMEIQSNAVFSSLPFLAMWLLSYVYLIAADVLLKKKIL 317
            ::|...:..:...||...:|:||..:|...:|.|...||||:|..||...:...|||.|..|...
Human   294 IVVAHFSYNWTFYTLLTLLPTYMKEILRFNVQENGFLSSLPYLGSWLCMILSGQAADNLRAKWNF 358

  Fly   318 SLTAVRKLFNTLSFWIPAAALIGIGFLSEENKNLAIVLMTVSVGVNSGATIGSSLNSIDLSPNHA 382
            |...||::|:.:....||..|:..||:..: .:||:..:|:|..:....:.|.|:|.:|::|::|
Human   359 STLCVRRIFSLIGMIGPAVFLVAAGFIGCD-YSLAVAFLTISTTLGGFCSSGFSINHLDIAPSYA 422

  Fly   383 GILIGLSNTVANVIPILTPLIAGEIVADKHNRG-QWQ 418
            |||:|::||.|.:..::.|:||..:..|   .| ||:
Human   423 GILLGITNTFATIPGMVGPVIAKSLTPD---AGVQWR 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9826	NP_611724.1	2A0114euk	14..450	CDD:129972	134/427 (31%)
CG9826	NP_611724.1	MFS	19..438	CDD:119392	133/422 (32%)
SLC17A5	NP_001369562.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24
		Dileucine internalization motif	22..23
		MFS_SLC17A5	42..458	CDD:340939	133/424 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148594
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D619250at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.950