DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9826 and cima-1

DIOPT Version :9

Sequence 1:	NP_611724.1	Gene:	CG9826 / 37625	FlyBaseID:	FBgn0034784	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_001294208.1	Gene:	cima-1 / 24104589	WormBaseID:	WBGene00018473	Length:	543	Species:	Caenorhabditis elegans

Alignment Length:	495	Identity:	116/495 - (23%)
Similarity:	206/495 - (41%)	Gaps:	64/495 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 HLQSFLLFLGLTVMHIARL------------NVSVAIVAMTNAATTNPNFPEFEWTEKQKSYILS 67
            |....:||..:.:|..|.|            |::||::.||:....... ...||..:|:..:|:
Worm    56 HSAHSVLFPSMRLMLAAMLCCCFITLSISSSNLAVALICMTSCPVHGYG-GTLEWQSQQEGLVLA 119

  Fly    68 SFYWGYILTLFPGSFLCRRYGAKVVLFVASCGTAVLSLMTPWCITWGGWQVFCAIRILQGLFQGV 132
            :...|.::.:..|.:..|..| |.::|:......:.:||.|...:...|....| ||..|.....
Worm   120 AQNAGSLIMIVTGMWADRLNG-KWMVFIGLLLCCIGNLMLPLLASKSFWFAVLA-RISIGASDAC 182

  Fly   133 IFPCVTEHLAMWSPPEERNRLGAFSYTGTDCGTVLAMFISGMIA--KGAM-GWPGISYVSGSLCA 194
            :.|.|...:..|.|..||.........|...||:..:..:|.:.  |..: |||.|.|:|.::..
Worm   183 LMPAVNSLITRWFPQAERPAAIGLISGGRQIGTLFILPTAGYLCTRKDILDGWPAIFYLSATISV 247

  Fly   195 AWCFLWLIFASNNATESRFVGEAECKYIES-----SLEHNEDFHGRTIPIPWRAIWTSVPFLALL 254
            .....|:.|.::...:...:...|.::||:     |:....|   ||..:|:.|:..|.|..|.:
Worm   248 LVTVFWIPFGADKPAKQICISSREKEFIETRIACESIGKRTD---RTRRVPYGAMLHSKPLWACI 309

  Fly   255 VTRCAETYGLSTLQAEIPSYMNGVLNMEIQSNAVFSSLPFLAMWLLSYVYLIAADVLLKKKILSL 319
            .......|.|..:...:|:||..||......|.:.::||.|.::|........:..|..|..|..
Worm   310 FALICHEYPLVIMLQFLPNYMRDVLEFAPTKNGIIAALPILCLFLSKTFSSSLSSYLTTKLRLDK 374

  Fly   320 TAVRKLFNTLSFWIPAAALIGIGFLSEENKNLAIVLMTVSVGVNSGATIGSSLNS-------IDL 377
            |.|.|.||.::....|..:..:.|.::|:..||:..:       .||.|.:.|::       :.:
Worm   375 TFVCKGFNAVASAGLAICISFVPFFNKESAFLAVFCL-------CGAMIFAGLHTPGVITAMVQI 432

  Fly   378 SPNHAGILIGLS------NTVANVIPILTPLI--AGEIVADKHNRGQWQIVFGLAAVIFFVGNVV 434
            :|..:||:.|.|      .::.|  .|||..|  :|.:.       :|.:||.::|::..:..:|
Worm   433 APAFSGIITGWSFFAVAWFSIGN--KILTKYIVQSGSVT-------EWGMVFRVSALVAALPVIV 488

  Fly   435 FIIWGTAKAQPWDAD-------DFLKPKDTESACEKPKIT 467
            |.|||:|..:.|.|.       .|.:|...:.:.|..:.|
Worm   489 FTIWGSADREWWAAPSSKCSVASFHRPSIRDRSREMSRAT 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9826	NP_611724.1	2A0114euk	14..450	CDD:129972	112/476 (24%)
CG9826	NP_611724.1	MFS	19..438	CDD:119392	105/453 (23%)
cima-1	NP_001294208.1	2A0114euk	63..506	CDD:129972	110/464 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28615
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.020