DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9825 and CG2003

DIOPT Version :9

Sequence 1:	NP_611723.3	Gene:	CG9825 / 37624	FlyBaseID:	FBgn0034783	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_651903.2	Gene:	CG2003 / 43761	FlyBaseID:	FBgn0039886	Length:	492	Species:	Drosophila melanogaster

Alignment Length:	485	Identity:	253/485 - (52%)
Similarity:	336/485 - (69%)	Gaps:	14/485 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 PVLGMRHVQALLIFLNITTVFIGRLNVGVSVVAMTNAETTNPNF--PEYDWTEAEKSYILSSFFW 71
            |.||:||:||.|:|..:....:.:|||.|:|||||| |||:.|.  |.|:|:|.:|||||||::|
  Fly    12 PRLGLRHLQAGLLFYGLAANTVLQLNVSVAVVAMTN-ETTSNNSDPPHYNWSEEKKSYILSSYYW 75

  Fly    72 GYILTQFLGGYLCKRFGVKSVMFWGVFGSGVCSALTPLFIGFGEWQAYCGIRVLMGLAQGVVFPC 136
            |..|.||..||||||||.|:|:|||..||.:.||||...:..|.|:|||.||:|.||.| |.:||
  Fly    76 GCALAQFPAGYLCKRFGSKAVLFWGTLGSSLLSALTTYGVYAGGWKAYCAIRLLQGLCQ-VTWPC 139

  Fly   137 IHQHLAKWSPPEERNRLGALSHTGIECGNVSAMFLSGMIAKSSLGWPGISYVSAGVAFFWCTLWF 201
            ||||||.|.|..||.||||.::||.:||||.||:.:||||.||||||||||.:||:...||.||.
  Fly   140 IHQHLANWCPTAERTRLGAFAYTGFDCGNVLAMYGAGMIASSSLGWPGISYSAAGLGLIWCGLWL 204

  Fly   202 VFAANHPTESRFIGENELIYIESSLKHNESYHATIIPIPWKAIWTSAPFLALLIVRCAENWGLST 266
            :..||..:::|||||.|..||...::.:|......:.||||.|:||.|..|||..|||::|||:|
  Fly   205 LLGANKASDARFIGEAEKAYIVGDIQRSERKGPKKMEIPWKGIFTSVPVYALLCARCADSWGLTT 269

  Fly   267 LQAEIPSYMNGVLDMDMKSNAFFSALPFLAMWCMSYIYLVVADVLLGKNSVSLTILRKTYNSIAF 331
            :|.|:|:|::|||.:||||||.|||||||.||.|.|:||::|||||.|..:|||.|||||.|||.
  Fly   270 MQTELPTYLSGVLKLDMKSNAVFSALPFLLMWVMCYVYLIIADVLLRKKWMSLTTLRKTYTSIAL 334

  Fly   332 WIPAATLVGIGFLDKEQKNFAIALMTISVGVNSAQTIGSVLNTIDLSKNHASILMGIVNTAANFV 396
            |.||:.::.:..:.:.||...:.|:|:||||:||.||||.|||||||.|||.||.|::::..|.:
  Fly   335 WAPASIMLSLVIVGEGQKTLVLVLVTLSVGVSSAATIGSELNTIDLSPNHAGILAGLMSSFTNLM 399

  Fly   397 PIVTPLVVGWIVKENSDRSQWQIVFIIASVIFFVGNCIYLVFGTAETQPW-DAEDYLQTQNPELA 460
            .::||||||.:|.:.|.||||||||.:|:.:.|.||.|:|::|||.|||| ::::..:...||
  Fly   400 ALLTPLVVGVLVTDPSQRSQWQIVFSLAAGVLFTGNVIFLIWGTAVTQPWNESKESRRELEPE-- 462

  Fly   461 NRPPMQALSFPINENSKE------KINSKS 484
             ..|.......|..::.:      |:|..|
  Fly   463 -EKPFHRAKLEIGTDNTDGNVVGLKLNCTS 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9825	NP_611723.3	2A0114euk	14..450	CDD:129972	243/438 (55%)
CG9825	NP_611723.3	MFS	54..438	CDD:119392	215/383 (56%)
CG2003	NP_651903.2	2A0114euk	23..456	CDD:129972	239/434 (55%)
CG2003	NP_651903.2	MFS	58..441	CDD:119392	215/383 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442667
Domainoid	1	1.000	42	1.000	Domainoid score	I12425
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	8.890