DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9825 and Slc17a5

DIOPT Version :9

Sequence 1:	NP_611723.3	Gene:	CG9825 / 37624	FlyBaseID:	FBgn0034783	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001009713.1	Gene:	Slc17a5 / 363103	RGDID:	1311388	Length:	495	Species:	Rattus norvegicus

Alignment Length:	459	Identity:	142/459 - (30%)
Similarity:	229/459 - (49%)	Gaps:	28/459 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 RHVQALLIFLNITTVFIGRLNVGVSVVAMTNAETT---------------------NPNFPEYDW 57
            |:..|||.|.....::..|:|:.|::|.|.::.:|                     |....:|.|
  Rat    39 RYNLALLAFCGFFVLYALRVNLSVALVDMVDSNSTLTDNRTSKECAEHSAPVKVHHNHTGKKYQW 103

  Fly    58 TEAEKSYILSSFFWGYILTQFLGGYLCKRFGVKSVMFWGVFGSGVCSALTPLFIGFGEWQAYCGI 122
            ....:.:||.|||:|||:||..|||:..|.|.|.::..|:.|:.|.:..|||....|. .|...:
  Rat   104 DAETQGWILGSFFYGYIVTQIPGGYMASRIGGKLLLGLGILGTAVFTLFTPLAADLGV-VALIVL 167

  Fly   123 RVLMGLAQGVVFPCIHQHLAKWSPPEERNRLGALSHTGIECGNVSAMFLSGMIAKSSLGWPGISY 187
            |.|.||.:||.||.:|...:.|:||.||::|..:|:.|.:.|.|.::.|||:|. ..:.|..:.|
  Rat   168 RALEGLGEGVTFPAMHAMWSSWAPPLERSKLLTISYAGAQLGTVISLPLSGIIC-YYMNWTYVFY 231

  Fly   188 VSAGVAFFWCTLWFVFAANHPTESRFIGENELIYIESSLKHNESYHATIIPIPWKAIWTSAPFLA 252
            :...|...|..||....::.|...:.|...|..||.||||:..|....   :||.:|..|.|..|
  Rat   232 LFGLVGIVWFILWMWIVSDTPETHKTISHYEKEYIVSSLKNQLSSQKV---VPWVSILKSLPLWA 293

  Fly   253 LLIVRCAENWGLSTLQAEIPSYMNGVLDMDMKSNAFFSALPFLAMWCMSYIYLVVADVLLGKNSV 317
            :::...:.||...||...:|:||..:|..:::.|.|.||||:...|....:....||.|..|.:.
  Rat   294 IVVAHFSYNWTFYTLLTLLPTYMKEILRFNVQENGFLSALPYFGCWLCMIVCGQAADYLRVKWNF 358

  Fly   318 SLTILRKTYNSIAFWIPAATLVGIGFLDKEQKNFAIALMTISVGVNSAQTIGSVLNTIDLSKNHA 382
            |...:|:.::.|....||..||..||:..:. :.|:|.:|||..:....:.|..:|.:|::.::|
  Rat   359 STISVRRIFSLIGMVGPAVFLVAAGFIGCDY-SLAVAFLTISTTLGGFASSGFSINHLDIAPSYA 422

  Fly   383 SILMGIVNTAANFVPIVTPLVVGWIVKENSDRSQWQIVFIIASVIFFVGNCIYLVFGTAETQPWD 447
            .||:||.||.|....::.|::...:..:|:.: :||.||.||:.|...|...:.:|...|.|.|.
  Rat   423 GILLGITNTFATIPGMIGPIIAKSLTPDNTIK-EWQTVFCIAAAINVFGAIFFTLFAKGEVQNWA 486

  Fly   448 AEDY 451
            ..|:
  Rat   487 LSDH 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9825	NP_611723.3	2A0114euk	14..450	CDD:129972	141/456 (31%)
CG9825	NP_611723.3	MFS	54..438	CDD:119392	125/383 (33%)
Slc17a5	NP_001009713.1	2A0114euk	30..491	CDD:129972	142/459 (31%)
Slc17a5	NP_001009713.1	MFS	99..478	CDD:119392	125/385 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342490
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840