DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9825 and CG3036

DIOPT Version :9

Sequence 1:	NP_611723.3	Gene:	CG9825 / 37624	FlyBaseID:	FBgn0034783	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster

Alignment Length:	515	Identity:	130/515 - (25%)
Similarity:	221/515 - (42%)	Gaps:	96/515 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 AETNKGPV------LGMRHVQALLIFLNITTVFIGRLNVGVSVVAM--------TNA-------- 45
            :.|.||.:      |..|.|..||..|.....:..|:|:.:::|.|        .||
  Fly     2 SNTEKGGLQRVRNFLSCRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNSTA 66

  Fly    46 --ETTNPN--------FPEYDWTEAEKSYILSSFFWGYILTQFLGGYLCKRFGVKSVMFWGVFGS 100
              .|.:|:        ||   |...:.:::|..||||||||:..||.|.:..|.:.|....:..:
  Fly    67 ANSTASPDGVDVYEERFP---WDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWA 128

  Fly   101 GVCSALTPLFIGFGEWQAYCGIRVLMGLAQGVVFPCIHQHLAKWSPPEERNRLGALSHTGIECGN 165
            .:.:.:|||.... .:.....:||::|...|..:|.||...|.|.||.||::
  Fly   129 SLLTLITPLAAHI-NYVVLIVVRVVLGFMLGASWPAIHPVAAVWIPPMERSK------------- 179

  Fly   166 VSAMFLSGMIAKSSL----------------GWPGISYVSAGVAFFWCTLWFVFAANHPTESRFI 214
                |:|.|:| |||                ||..:.|::..|...|...||.|....|.....|
  Fly   180 ----FMSNMMA-SSLGAAITMPICGYLISVAGWASVFYLTGAVGLLWSLAWFTFVYETPATHPRI 239

  Fly   215 GENELIYIESSL-----KHNESYHATIIPIPWKAIWTSAPFLALLIVRCAENWGLSTLQAEIPSY 274
            ...|...||.::     |...|:      :||..:..|....|::|......:|..|:..::|::
  Fly   240 SAEERREIEEAIGTTTSKKRPSH------VPWGQLLCSPAVWAIIICHGLAVFGFFTVVNQLPTF 298

  Fly   275 MNGVLDMDMKSNAFFSALPFLAMWCMSYIYLVVADVLLGKNSVSLTILRKTYNSIAFWIPAATLV 339
            |:.:|..|:|.|..||:||:|..:.|:.....:||.|..|.::|.|..||.:.:.|..||...::
  Fly   299 MSKILHFDIKQNGLFSSLPYLGKYVMAVASSYLADYLRKKGTLSTTATRKLFTTFALVIPGLLMI 363

  Fly   340 GIGFLDKEQKNFAIALMTISVGVNSAQTIGSVLNTIDLSKNHASILMGIVNTAANFVPIVTPLVV 404
            ...||..: ..:::.:.::::..:.|.|.|.:.|.:|::.|....:.|:.||.::|...::..:|
  Fly   364 VQVFLGYD-ATWSVTIFSLALFAHGAVTAGYLGNGLDIAPNFGGTIFGLANTLSSFGGFLSTSMV 427

  Fly   405 GWIVKENSDRSQWQIVFIIASVIFFVGNCIYLVFGTAETQPWDAEDYLQTQNPELANRPP 464
            |.:..::.....|||||.|.:..:.....::.:.|:.|.|||              |.||
  Fly   428 GALTYKDQSFHSWQIVFWILAATYISAAVVFAILGSGELQPW--------------NNPP 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9825	NP_611723.3	2A0114euk	14..450	CDD:129972	123/482 (26%)
CG9825	NP_611723.3	MFS	54..438	CDD:119392	103/404 (25%)
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	126/498 (25%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	105/406 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	8.970