DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9825 and MFS18

DIOPT Version :9

Sequence 1:	NP_611723.3	Gene:	CG9825 / 37624	FlyBaseID:	FBgn0034783	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_608835.1	Gene:	MFS18 / 33650	FlyBaseID:	FBgn0025684	Length:	439	Species:	Drosophila melanogaster

Alignment Length:	465	Identity:	120/465 - (25%)
Similarity:	188/465 - (40%)	Gaps:	87/465 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 RHVQALLIFLNIT---TVFIGRLNVGVSVVAMTNAETTNPNFPEYDWTEAEKSYILSSFFWGYIL 75
            ||.:.:.....||   .::..|..:.:.|.|:.:|:         .|::.:...:||||||||.|
  Fly    23 RHEKRVWFITLITGTCMLYSTRTTMPLLVPAVASAQ---------KWSKTDSGTVLSSFFWGYTL 78

  Fly    76 TQFLGGYLCKRFGVKSVMFWGVFGSGVCSALTPLFIGFGEWQA----------YCGIRVLMGLAQ 130
            ||.:|||...|||.:.|:.:...|..:.:.|.|..|    |.|          ...||:|.|..|
  Fly    79 TQVVGGYFSDRFGGQRVILFAAIGWSLITFLMPTII----WTAGSIKSYAIPFIVAIRILNGALQ 139

  Fly   131 GVVFPCIHQHLAKWSPPEERNRLGALSHTGIECGNVSAMFLSGMIAKSSLGWPGISYV-----SA 190
            ||.||.:....::...|.||:....|    :..|:.....|:|::....|.:.|.|||     ..
  Fly   140 GVHFPSMISLTSQNLCPNERSSFFGL----LTAGSALGTLLTGIMGSFLLDYFGWSYVFRVIGLM 200

  Fly   191 GVAFFWCTLWFVFAANHPTESRFIGE-NELIYI--ESSLKHNESYHATIIPIPWKAIWTSAPFLA 252
            |:|:.....::..|          || |.:|.|  .|.|..|:| .|....:||...:....|.|
  Fly   201 GIAWALVLRYYAMA----------GERNRIINIATPSRLCANKS-PAETSAVPWLRYFRRLSFWA 254

  Fly   253 LLIVRCAENWGLSTLQAEIPSYMNGVLDMDMKSNAFFSALPFLAMWCMSYI-------------Y 304
            .::....|......|.:.:|:|             |....|....|.::.|             |
  Fly   255 CVLTHACEMNCFFVLLSWLPTY-------------FHDGFPHAKGWVVNMIPWLALPPCTLFAKY 306

  Fly   305 LVVADVLLGKNSVSLTILRKTYNSIAFWIPAATLVGIGFLDKEQKNFAIAL--MTISVGVNSAQT 367
            |...  ||.:...:.|: ||...|..|   ||..:.: |:.....:|..||  |||.:|......
  Fly   307 LTTR--LLAREWHTTTV-RKVIQSCCF---AAQNLAL-FVMSRTSDFHTALICMTIIIGGTGFHN 364

  Fly   368 IGSVLNTIDLSKNHASILMGIVNTAANFVPIVTPLVVGWIVKENSDRSQWQIVFIIASVIFFVGN 432
            ....:|..||:..|:..:.|::||.......:...:.|.|::..   ..|.:||..|:.|..||.
  Fly   365 NAVTVNPQDLAPLHSGSVFGLMNTVGAIPGFLGVYLAGHILELT---QSWPMVFSAAAGINLVGW 426

  Fly   433 CIYLVFGTAE 442
            .|::|||:||
  Fly   427 IIFIVFGSAE 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9825	NP_611723.3	2A0114euk	14..450	CDD:129972	120/465 (26%)
CG9825	NP_611723.3	MFS	54..438	CDD:119392	107/416 (26%)
MFS18	NP_608835.1	MFS	30..432	CDD:119392	113/452 (25%)
MFS18	NP_608835.1	MFS_1	32..397	CDD:284993	103/412 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452001
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.890