DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9825 and MFS17

DIOPT Version :9

Sequence 1:	NP_611723.3	Gene:	CG9825 / 37624	FlyBaseID:	FBgn0034783	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001015096.2	Gene:	MFS17 / 3354861	FlyBaseID:	FBgn0058263	Length:	505	Species:	Drosophila melanogaster

Alignment Length:	478	Identity:	133/478 - (27%)
Similarity:	223/478 - (46%)	Gaps:	46/478 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LLIFLN---ITTVFIGRLNVGVSVVAM--TNAETTNPNFPEY---------DWTEAEKSYILSSF 69
            :|.||:   ....|:.|.::..::|||  .:..|.|.:..:.         |.....||.::|||
  Fly    38 VLYFLSWSGFLVSFMMRNDMNFALVAMIANDNSTQNQSLIKSQQILGTGTDDQKTIVKSVVISSF 102

  Fly    70 FWGYILTQFLGGYLCKRFGVKSVMFWGVFGSGVCSALTPLFIGFGEWQAYCGIRVLMGLAQGVVF 134
            :|.|:|:|.:||...:.||.|.|..|....:.:||.:.|..... .:.|...:|.:.|.|.|:.:
  Fly   103 YWCYVLSQVVGGVATELFGTKCVFGWSQLATALCSFMMPSAAQL-HYIAVIVLRSIQGFASGLTW 166

  Fly   135 PCIHQHLAKWSPPEERNRLGALSHTGIECGNVSAMFLSGMIAKSSLGWPGISYVSAGVAFFWCTL 199
            |.::..:..|.|..||:|..: |..|...|......|.|.|. |..|||.|.|.:..:...||.|
  Fly   167 PAMYAIVGYWIPLTERSRFMS-SFQGFSIGIGLTYPLCGFIL-SEWGWPYIFYTTGTLGLGWCIL 229

  Fly   200 WFVFAANHPTESRFIGENELIYIESSLKHNESYHATIIPIPWKAIWTSAPFLALLIVRCAENWGL 264
            |::.|.|.|.|...|.::||.|||.::| .|...:..:.:||..|:.|.|..|:.|......:..
  Fly   230 WYLLAFNTPREHPRITKDELNYIELNVK-KEVNSSVKVKVPWLQIFKSIPAWAIAITTFGRIFVH 293

  Fly   265 STLQAEIPSYMNGVLDMDMKSNAFFSALPFLAMWCMSYIYLVVADVLLGKNSVSLTILRKTYNSI 329
            .......|::|..||..:.::|.|.|.:||:..:..|.::..:||.::....:.||.:||.:.::
  Fly   294 YIFIVNGPTFMGNVLKFNFETNGFLSGVPFICSYISSVLFCYIADKIVFYKVLCLTNVRKVFTAL 358

  Fly   330 AFWIPAATLVGIGFLDKEQKNFAIALMT--ISVGVNSAQTIGSVLNTIDLSKN--HASILMGIVN 390
            :..||...:..||::|    |..|.|..  |:|...:|...|::.|.|||:.|  |::.::....
  Fly   359 SQIIPGVLIYCIGYID----NVYILLTVWFIAVIFITASYAGAMANIIDLAPNYGHSAAVLAFCQ 419

  Fly   391 TAANFVPIVTPLVVGWIVKENSDRSQWQIVFIIASVIFFVGNCIYLVFGTAETQPWDAEDYLQTQ 455
            |.......::||..|:||.:.....||:.||.::::|..:....|.:|||||.|.|:.
  Fly   420 TIHMSASFISPLTAGFIVTQEDSIDQWRRVFEVSAIISILTYLFYQLFGTAEIQTWNK------- 477

  Fly   456 NPELANRPPMQALSFPINENSKE 478
                         ..|:|::|.|
  Fly   478 -------------GLPVNDDSDE 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9825	NP_611723.3	2A0114euk	14..450	CDD:129972	129/448 (29%)
CG9825	NP_611723.3	MFS	54..438	CDD:119392	112/396 (28%)
MFS17	NP_001015096.2	2A0114euk	34..477	CDD:129972	129/446 (29%)
MFS17	NP_001015096.2	MFS	41..467	CDD:119392	121/433 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	8.970