DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9825 and MFS3

DIOPT Version :9

Sequence 1:	NP_611723.3	Gene:	CG9825 / 37624	FlyBaseID:	FBgn0034783	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_608572.1	Gene:	MFS3 / 33292	FlyBaseID:	FBgn0031307	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	524	Identity:	156/524 - (29%)
Similarity:	247/524 - (47%)	Gaps:	73/524 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTAET-NKGPVLG----MRHVQALLIFLNITTVFIGRLNVGVSVVAMTN---------------- 44
            ||.|. .||.:||    .|:|.|||..:.:..|:..::|:.|::|||.|
  Fly     1 MTDEVPAKGSILGKLVPARYVLALLGSIGMAIVYGLKVNLSVAMVAMVNHTAIKAHGDGGGHGGH 65

  Fly    45 -------------AETTNPNFP-------------EYDWTEAEKSYILSSFFWGYILTQFLGGYL 83
                         .|..||  |             .:||:|..:..:||.:||||:::|....::
  Fly    66 GSVILSNASQVSLVEECNP--PGGASNVTAKVEDGPFDWSEPLQGTLLSCYFWGYLVSQIPLAHV 128

  Fly    84 CKRFGVKSVMFWGVFGSGVCSALTPLFIGFGEWQAYCGI---RVLMGLAQGVVFPCIHQHLAKWS 145
            .:.|..|.||.:.|..:.||:.|||:|...    .|.|:   |||.|:..|..||.:|..:|.|:
  Fly   129 AENFSAKWVMLFSVAINVVCTLLTPVFTEL----HYGGLILMRVLEGVGGGASFPAMHVMIASWA 189

  Fly   146 PPEERNRLGALSHTGIECGNVSAMFLSGMIAKSSLGWPGISYVSAGVAFFWCTLWFVFAANHPTE 210
            ||.||..:..:.:.|...|...::.|:| :..:..||..:.||...::..|..||.:...::|.:
  Fly   190 PPTERMVMSTIIYVGTSAGTALSILLAG-VCSAQWGWESVFYVMGALSCIWMLLWVILVQDNPNK 253

  Fly   211 SRFIGENELIYIESSL--KHNESYHATIIPIPWKAIWTSAPFLALLIVRCAENWGLSTLQAEIPS 273
            .|||...|...|.|||  :....:|..   :||..::||.||.|:||.....|:|......|||.
  Fly   254 QRFISLEERQMITSSLGTEQKTEHHPA---VPWGKVFTSVPFWAILIAHTCSNFGWYMFLIEIPF 315

  Fly   274 YMNGVLDMDMKSNAFFSALPFLAMWCMSYIYLVVADVLLGKNSVSLTILRKTYNSIAFWIPAATL 338
            ||..||..::.|||..||||:..|...|.....:.|.|..|..::.|:.|||..||...||...|
  Fly   316 YMKQVLKFNVASNAALSALPYFPMIIFSICLGKLLDSLQAKGKITTTVARKTATSICTLIPGVCL 380

  Fly   339 VGIGFLDKEQKNFAIALMTISVGVNSAQTIGSVLNTIDLSKNHASILMGIVNTAANFVPIVTPLV 403
            :.:.::...... |:::|::.:....:...|.:.|.||::.|.|..|:.:.||||....||.||.
  Fly   381 LVLCYIGCRHYE-AVSVMSVGIVAMGSMFSGFLSNHIDIAPNFAGTLVALTNTAATLPGIVVPLF 444

  Fly   404 VGWIVKENSDRSQWQIVFIIASVIFFVGNCIYLVFGTAETQPW---------DAEDYLQTQNPEL 459
            ||::.|.|.:...|:|:|.:..|:|.:...:::..|:...|||         :|:|. :|...||
  Fly   445 VGFVTKGNQNIGAWRIIFGVTIVLFALEFLVFVFLGSGSEQPWNKAGTPKDPEAKDE-KTPLKEL 508

  Fly   460 ANRP 463
            ..:|
  Fly   509 PTKP 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9825	NP_611723.3	2A0114euk	14..450	CDD:129972	144/491 (29%)
CG9825	NP_611723.3	MFS	54..438	CDD:119392	123/388 (32%)
MFS3	NP_608572.1	2A0114euk	19..489	CDD:129972	143/480 (30%)
MFS3	NP_608572.1	MFS	100..479	CDD:119392	123/387 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D46132at33392
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	8.970