DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9825 and SPAC11D3.18c

DIOPT Version :9

Sequence 1:	NP_611723.3	Gene:	CG9825 / 37624	FlyBaseID:	FBgn0034783	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001342807.1	Gene:	SPAC11D3.18c / 2543005	PomBaseID:	SPAC11D3.18c	Length:	498	Species:	Schizosaccharomyces pombe

Alignment Length:	463	Identity:	110/463 - (23%)
Similarity:	190/463 - (41%)	Gaps:	98/463 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 PVLGMRHVQALLIFLNITTVFIGRLNVGVSVVAMTNAETTNPNFPEYDWTEAEKSY------ILS 67
            |::|..::.|          |:.|.|:|.:.||              ..|||...|      .:|
pombe    63 PIIGFLYLMA----------FLDRSNIGNAAVA--------------GMTEALSLYGERLNVAVS 103

  Fly    68 SFFWGYILTQFLGGYLCKRFGVKSVMFWGVFGSGVCSALTPLFIGFGEWQAYCGI---RVLMGLA 129
            .|:..|||.:.....|.||.....::.:..|    ..::|.||.||  ..:|.|:   |:::||.
pombe   104 IFYVLYILVETPSVVLVKRIKASRMLAFISF----AWSMTVLFSGF--MSSYGGLIATRLILGLL 162

  Fly   130 QGVVFPCIHQHL-AKWSPPEERNRLGAL-SHTGI--ECGNVSAMFLSGMIAKSSLGWPGISYVSA 190
            :|.:||.::.:| ..::..|:..||..| :..|:  ..|.:.|..|..:.|.:..||..|..|..
pombe   163 EGCLFPALNLYLTTHYTRKEQCQRLSYLFASAGLAGAFGGLFAYALEQVHAGNKEGWQWIYIVEG 227

  Fly   191 GVAFFWCTLWFVFAANHPTESRFI---GENELIYIESSLKHNESYHATIIPIPW----KAIWTSA 248
            .|:|....| .:||.....|:.:.   .|.|:..|...:  |..||.. ....|    ||.....
pombe   228 LVSFIGVPL-CLFALPDKMENAWFLTREEREVAIIRRDI--NARYHGE-QHFEWSEVRKAFKDPK 288

  Fly   249 PFLALLIVRCAEN--WGLSTLQAEIPSYMNGVLDMDMKSNAFFSALPFLAMWCMSYIYLV-VADV 310
            .:::.....||:.  :|.|:.   :|..:.|:..:.:::|  :..:|......:|::::. ::|
pombe   289 VYVSATSQFCADMVLYGFSSF---LPVIIKGLGFVGLQTN--YMTIPVYIAGVISFLFVAWLSD- 347

  Fly   311 LLGKNSVSLTILRKTYNSIAFWIPAATLVGIGFL-----DKEQKNFAIALMTISVGVNSAQTIGS 370
                    .|.||..|     .|.|:|:|.:|::     |.....:. |...|::|.    .||.
pombe   348 --------RTQLRAVY-----LISASTVVAVGYIIMLASDSNAAKYT-ATYIIAIGC----YIGP 394

  Fly   371 VLNTIDLSKNHA-----SILMGIVNTAANFVPIVTPLVVGWIVK-ENSDRSQWQIVFIIASVIFF 429
            .||...|:.|.|     :..:||..|.||    .:.:|.|.|.: :|:.:......|.:..||
pombe   395 GLNLGWLNNNVAGHYKRATAIGIQQTLAN----SSGIVAGQIYRSKNAPKYILGNAFTLGCVI-- 453

  Fly   430 VGNCIYLV 437
            ||...|:|
pombe   454 VGGLAYVV 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9825	NP_611723.3	2A0114euk	14..450	CDD:129972	108/458 (24%)
CG9825	NP_611723.3	MFS	54..438	CDD:119392	101/418 (24%)
SPAC11D3.18c	NP_001342807.1	UhpC	68..461	CDD:332119	107/456 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050