DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9825 and Slc17a5

DIOPT Version :9

Sequence 1:	NP_611723.3	Gene:	CG9825 / 37624	FlyBaseID:	FBgn0034783	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_766361.1	Gene:	Slc17a5 / 235504	MGIID:	1924105	Length:	495	Species:	Mus musculus

Alignment Length:	470	Identity:	144/470 - (30%)
Similarity:	231/470 - (49%)	Gaps:	29/470 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ETNKGPV-LGMRHVQALLIFLNITTVFIGRLNVGVSVVAMTNAETT------------------- 48
            :|...|| ...|:..|:|.|.....::..|:|:.|::|.|.::.||
Mouse    28 QTEAAPVCCSARYNLAILAFCGFFVLYALRVNLSVALVDMVDSNTTLTDNRTSKECAEHSAPIKV 92

  Fly    49 --NPNFPEYDWTEAEKSYILSSFFWGYILTQFLGGYLCKRFGVKSVMFWGVFGSGVCSALTPLFI 111
              |....:|.|....:.:||.|||:|||:||..|||:..|.|.|.::..|:.|:.|.:..|||..
Mouse    93 HHNHTGKKYKWDAETQGWILGSFFYGYIVTQIPGGYIASRVGGKLLLGLGILGTSVFTLFTPLAA 157

  Fly   112 GFGEWQAYCGIRVLMGLAQGVVFPCIHQHLAKWSPPEERNRLGALSHTGIECGNVSAMFLSGMIA 176
            ..|. .....:|.|.||.:||.||.:|...:.|:||.||::|..:|:.|.:.|.|.::.|||:|.
Mouse   158 DLGV-VTLVVLRALEGLGEGVTFPAMHAMWSSWAPPLERSKLLTISYAGAQLGTVISLPLSGIIC 221

  Fly   177 KSSLGWPGISYVSAGVAFFWCTLWFVFAANHPTESRFIGENELIYIESSLKHNESYHATIIPIPW 241
             ..:.|..:.|:...|...|..||....::.|...:.|...|..||.||||:..|....   :||
Mouse   222 -YYMNWTYVFYLFGIVGIVWFILWMWIVSDTPETHKTISHYEKEYIVSSLKNQLSSQKV---VPW 282

  Fly   242 KAIWTSAPFLALLIVRCAENWGLSTLQAEIPSYMNGVLDMDMKSNAFFSALPFLAMWCMSYIYLV 306
            .:|..|.|..|:::...:.||...||...:|:||..:|..:::.|.|.||||:...|....:...
Mouse   283 GSILKSLPLWAIVVAHFSYNWSFYTLLTLLPTYMKEILRFNVQENGFLSALPYFGCWLCMILCGQ 347

  Fly   307 VADVLLGKNSVSLTILRKTYNSIAFWIPAATLVGIGFLDKEQKNFAIALMTISVGVNSAQTIGSV 371
            .||.|..|.:.|...:|:.::.:....||..||..||:..:. :.|:|.:|||..:....:.|..
Mouse   348 AADYLRVKWNFSTISVRRIFSLVGMVGPAVFLVAAGFIGCDY-SLAVAFLTISTTLGGFASSGFS 411

  Fly   372 LNTIDLSKNHASILMGIVNTAANFVPIVTPLVVGWIVKENSDRSQWQIVFIIASVIFFVGNCIYL 436
            :|.:|::.::|.||:||.||.|....:..|::...:..:|:.| :||.||.||:.|...|...:.
Mouse   412 INHLDIAPSYAGILLGITNTFATIPGMTGPIIAKSLTPDNTIR-EWQTVFCIAAAINVFGAIFFT 475

  Fly   437 VFGTAETQPWDAEDY 451
            :|...|.|.|...|:
Mouse   476 LFAKGEVQSWALSDH 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9825	NP_611723.3	2A0114euk	14..450	CDD:129972	140/456 (31%)
CG9825	NP_611723.3	MFS	54..438	CDD:119392	124/383 (32%)
Slc17a5	NP_766361.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..25
		Dileucine internalization motif. /evidence=ECO:0000250	22..23
		2A0114euk	30..491	CDD:129972	143/468 (31%)
		MFS	99..478	CDD:119392	124/385 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838701
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840