DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9825 and Slc17a8

DIOPT Version :9

Sequence 1:	NP_611723.3	Gene:	CG9825 / 37624	FlyBaseID:	FBgn0034783	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_892004.1	Gene:	Slc17a8 / 216227	MGIID:	3039629	Length:	601	Species:	Mus musculus

Alignment Length:	476	Identity:	142/476 - (29%)
Similarity:	226/476 - (47%)	Gaps:	30/476 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 RHVQALLIFLNITTVFIGRLNVGVSVVAMTNAETT----NPNF--PEYDWTEAEKSYILSSFFWG 72
            |::.|::..|.....|..|.|:||::|.|.|..|.    .|..  .:::|.......|..|||||
Mouse    88 RYIIAVMSGLGFCISFGIRCNLGVAIVEMVNNSTVYVDGKPEIQTAQFNWDPETVGLIHGSFFWG 152

  Fly    73 YILTQFLGGYLCKRFGVKSVMFWGVFGSGVCSALTP--LFIGFGEWQAYCGIRVLMGLAQGVVFP 135
            ||:||..||::..:|....|....:|.:...:...|  ..:.:|   ...|:|:|.||.:||.:|
Mouse   153 YIVTQIPGGFISNKFAASRVFGAAIFLTSTLNMFIPSAARVHYG---CVMGVRILQGLVEGVTYP 214

  Fly   136 CIHQHLAKWSPPEERNRLGALSHTGIECGNVSAMFLSGMIAKSSLGWPGISYVSAGVAFFWCTLW 200
            ..|...:||:||.||:||...|..|...|.|.||.|:|::.: .:||..:.|:.......|...|
Mouse   215 ACHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGVLVQ-YIGWASVFYIYGMFGIIWYMFW 278

  Fly   201 FVFA----ANHPTESRFIGENELIYIESSLKHNESYHA-TIIPIPWKAIWTSAPFLALLIVRCAE 260
            .:.|    |.|||    |...|..|||:|:....:..: :....||:..:||.|..|:::.....
Mouse   279 LLQAYECPAAHPT----ISNAERTYIETSIGEGANLASLSKFNTPWRRFFTSLPVYAIIVANFCR 339

  Fly   261 NWGLSTLQAEIPSYMNGVLDMDMKSNAFFSALPFLAMWCMSYIYLVVADVLLGKNSVSLTILRKT 325
            :|....|....|:|...|....:......||:|.:.|..:..|...:||.|..:..::.|.:||.
Mouse   340 SWTFYLLLISQPAYFEEVFGFAISKVGLLSAVPHMVMTIVVPIGGQLADYLRSRKILTTTAVRKI 404

  Fly   326 YNSIAFWIPAATLVGIGFLDKEQKNFAIALMTISVGVNSAQTIGSVLNTIDLSKNHASILMGIVN 390
            .|...|.:.|..|:.:||  ...|..||:.:.::||.:.....|..:|.:|::..:|||||||.|
Mouse   405 MNCGGFGMEATLLLVVGF--SHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISN 467

  Fly   391 TAANFVPIVTPLVVGWIVKENSDRSQWQIVFIIASVIFFVGNCIYLVFGTAETQPW-DAEDYLQT 454
            .......:|.||:||.:.|..: |.:||.||:||:::.:.|...|.||.:.|.|.| |.|:..:.
Mouse   468 GVGTLSGMVCPLIVGAMTKHKT-REEWQNVFLIAALVHYSGVIFYGVFASGEKQDWADPENLSED 531

  Fly   455 Q-----NPELANRPPMQALSF 470
            :     ..|||....:...:|
Mouse   532 KCGIIDQDELAEETELNHETF 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9825	NP_611723.3	2A0114euk	14..450	CDD:129972	137/449 (31%)
CG9825	NP_611723.3	MFS	54..438	CDD:119392	118/390 (30%)
Slc17a8	NP_892004.1	2A0114euk	88..526	CDD:129972	137/448 (31%)
		MFS	93..515	CDD:119392	130/432 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	576..601
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I11710
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820