DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9825 and slc-17.9

DIOPT Version :9

Sequence 1:	NP_611723.3	Gene:	CG9825 / 37624	FlyBaseID:	FBgn0034783	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001379067.1	Gene:	slc-17.9 / 181189	WormBaseID:	WBGene00011643	Length:	516	Species:	Caenorhabditis elegans

Alignment Length:	466	Identity:	110/466 - (23%)
Similarity:	200/466 - (42%)	Gaps:	55/466 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 ALLIFLNITTVFIGRLNVGVSVVAMTNAETTNPNFP---------------EYDWTEAEKSYILS 67
            :.|:.|....:.||..|:..|:|.|.....||...|               ::.|:..::..|.|
Worm    25 SFLLCLCFVALAIGTSNISQSMVCMVKKPDTNYTCPLAEPEVEAIPCNHPKQFAWSSIQQGLIYS 89

  Fly    68 SFFWGYILTQFLGGYLCKRFGVKSVMFWGVFGSG----VCSALTPLFIGFGEWQAYCGIRVLMGL 128
            ...:| .|...:.|:...|...|    |.:..:.    |.:|:.|:..| ..:.....:|||.|.
Worm    90 GQNFG-SLFMVITGWQADRLNGK----WTIVAAMAFIIVSNAVLPISAG-ASFALVFFLRVLTGF 148

  Fly   129 AQGVVFPCIHQHLAKWSPPEER-NRLGALSHTGIECGNVSAMFLSGMI-----AKSSLGWPGISY 187
            ...::.|.....:.:|.||:|| :.||.:: :|.:.|.:..:.:.|.:     :|...|||.|.|
Worm   149 GDALLSPASSSLITRWFPPKERPSALGIVT-SGRQIGTLIILPIGGWLCGSDGSKFLGGWPAIFY 212

  Fly   188 VSAGVAFFWCTLWFVFAANHPTESRFIGENELIYIESSL------KHNESYHATIIPIPWKAIWT 246
            :|:.||.....:|.||:|:.|::...|..||..||...:      |.|...:.     |||||:|
Worm   213 LSSVVAAAVLVIWVVFSADKPSKHLCISHNEEAYINRKIEEENIGKRNNRKNT-----PWKAIFT 272

  Fly   247 SAP-FLALLIVRCAENWGLSTLQAEIPSYMNGVLDMDMKSNAFFSALPFLAMWCMSYIYLVVADV 310
            |.. ::|:..:.|.| :.|..:...:|.:.:.||.:....|...||||...::....:...:|..
Worm   273 SKQVWVAVAALVCHE-FPLVIMLQFLPKFFSDVLGLSNTVNGLVSALPMAILFLSKCLSASLASY 336

  Fly   311 LLGKNSVSLTILRKTYNSIA-----FWIPAATLVGIGFLDKEQKNFAIALMTISVGVNSAQTIGS 370
            |.....:..|...|.:|.||     ..|.|..|:.    :.:...:||.::.::.......|.|.
Worm   337 LTANGYLRKTQSCKIFNFIASLGLGICIAATPLMS----NLQHAIWAIIILCLANAFAGLHTPGV 397

  Fly   371 VLNTIDLSKNHASILMGIVNTAANFVPIVTPLVVGWIVKENSDRSQWQIVFIIASVIFFVGNCIY 435
            :...:.|:...:.|:.|:....|:...|...|::..|::..| :.:|.|||.|::.:..:....:
Worm   398 LTAIVQLAPAFSGIITGLAFAVASCFSIFNKLLISQILRTGS-KHEWTIVFEISAFVAILPTIFF 461

  Fly   436 LVFGTAETQPW 446
            .::|:||...|
Worm   462 TLWGSAERTEW 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9825	NP_611723.3	2A0114euk	14..450	CDD:129972	110/466 (24%)
CG9825	NP_611723.3	MFS	54..438	CDD:119392	95/405 (23%)
slc-17.9	NP_001379067.1	2A0114euk	5..474	CDD:129972	110/466 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28615
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.920