DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9825 and M117.1

DIOPT Version :9

Sequence 1:	NP_611723.3	Gene:	CG9825 / 37624	FlyBaseID:	FBgn0034783	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_502234.2	Gene:	M117.1 / 178112	WormBaseID:	WBGene00010918	Length:	523	Species:	Caenorhabditis elegans

Alignment Length:	480	Identity:	103/480 - (21%)
Similarity:	202/480 - (42%)	Gaps:	64/480 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LGMRHVQALLIFLNITTVFIGRLN--VGVSVVAMTNAETTNPNFPE------YDWTEAEKSYILS 67
            |.|:|....:||: :|.:.:|.:.  |.|...:|...|..:....|      |.:|..|||.::|
Worm    70 LSMKHRIRWVIFI-LTWLQLGSVMNCVDVFSFSMVYMEKNSTIAAEAGLDDIYIYTLEEKSSLIS 133

  Fly    68 SFFWGYILTQFLGGYLCKRFGVKSVMFWGVFGSGVCSALTPLFIGFGEW------QAYCGIRVLM 126
            :...|.::..:....|.:::|.:.|:   .|.|.:|:.:|    .|..|      ......|:..
Worm   134 AMAIGSLIGMYPQNVLMQKYGPRLVL---TFASLLCAVVT----AFMPWALDTNYHVALVFRIFQ 191

  Fly   127 GLAQGVVFPCIHQHLAKWSPPEERN-RLGALSHTGIECGN-VSAMFLSGMIAKSSLGWPGISYVS 189
            |:.....|..:....:||||.:|.. .|.|||  |..... |..:.|:|. ..|::||..|.|:.
Worm   192 GILYSADFGVVGYVCSKWSPIKEVGMSLAALS--GFTAARAVIQLPLAGW-TTSNVGWRPIYYIL 253

  Fly   190 AGVAFFWCTLWFVFAANHPTESRFIGENELIYIESSLKHNESYHATIIPIPWKAIWTSAPFLALL 254
            :.:.|....:||:|..:.|.:...:..:||.:|....|.:::...     |::.:.|.....|:.
Worm   254 SIILFISTIIWFLFYRDDPEDHCLMTHHELQHIGGGTKRDKTKKT-----PYREVLTDKSVWAVW 313

  Fly   255 IVRCAENWGLSTLQAEIPSYMNGV-----LDMDMKSNAFFSALPFLAMWCMSYIYLVVADVLLGK 314
            :.      |.:.:.|.....:.|.     |.||:::||:.:::       ..|:::.|. |..|.
Worm   314 VA------GFADIFASFVFLVYGAQYYQYLGMDIQANAWLNSM-------KGYLFIGVR-VFAGI 364

  Fly   315 NSVSLTIL-----RKTYNSIAFWIPAATLVGIGFLDKEQKNFAIALMTI---SVGVNSAQTIGSV 371
            .|..:..|     .:.:|:|:..:||..|:.:..|.:|.....:..:|.   |.|.|..   |..
Worm   365 ASDRIRTLPEKSKLRLFNTISLQVPAFFLMLVVLLPREHPYLHVICITFYQASFGFNCG---GFY 426

  Fly   372 LNTIDLSKNHASILMGIVNTAANFVPIVTPLVVGWIVKENSDRSQ--WQIVFIIASVIFFVGNCI 434
            .....:|:..:..::|.:....:...::.|::...:|...|:.|:  |...|:|.::...|.|.:
Worm   427 KGAALISRQFSYFVIGYIQLFKSLATLLEPVLFSLLVLPGSEDSELSWTSYFLIHALTLTVANTV 491

  Fly   435 YLVFGTAETQPWDAEDYLQTQNPEL 459
            |::...:|...:.....|:...|:|
Worm   492 YVLLARSEPADFVLNAELELSKPQL 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9825	NP_611723.3	2A0114euk	14..450	CDD:129972	98/466 (21%)
CG9825	NP_611723.3	MFS	54..438	CDD:119392	88/412 (21%)
M117.1	NP_502234.2	2A0114euk	66..499	CDD:129972	99/461 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820