DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9825 and Slc17a6

DIOPT Version :9

Sequence 1:	NP_611723.3	Gene:	CG9825 / 37624	FlyBaseID:	FBgn0034783	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_543129.3	Gene:	Slc17a6 / 140919	MGIID:	2156052	Length:	582	Species:	Mus musculus

Alignment Length:	457	Identity:	143/457 - (31%)
Similarity:	219/457 - (47%)	Gaps:	30/457 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LGMRHVQALLIFLNITTVFIGRLNVGVSVVAMTNAETTN------PNFPEYDWTEAEKSYILSSF 69
            |..|::.|::..|.....|..|.|:||::|.|.|..|.:      ....:::|.......|..||
Mouse    67 LPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNWDPETVGMIHGSF 131

  Fly    70 FWGYILTQFLGGYLCKRFGVKSVMFWGVFGSGV--CSALTPLFIGFGEWQAYCGI--RVLMGLAQ 130
            |||||:||..|||:..|.....     |||:.:  .|.|..|..........|.|  |:|.||.:
Mouse   132 FWGYIITQIPGGYIASRLAANR-----VFGAAILLTSTLNMLIPSAARVHYGCVIFVRILQGLVE 191

  Fly   131 GVVFPCIHQHLAKWSPPEERNRLGALSHTGIECGNVSAMFLSGMIAKSSLGWPGISYVSAGVAFF 195
            ||.:|..|...:||:||.||:||...|..|...|.|.||.|:|::.:.: ||..:.||.......
Mouse   192 GVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYT-GWSSVFYVYGSFGMV 255

  Fly   196 WCTLWFVFA----ANHPTESRFIGENELIYIESSLKHNESYHATI--IPIPWKAIWTSAPFLALL 254
            |...|.:.:    |.|||    |.:.|..|||.|:..:.:....:  ...||:..:||.|..|::
Mouse   256 WYMFWLLVSYESPAKHPT----ITDEERRYIEESIGESANLLGAMEKFKTPWRKFFTSMPVYAII 316

  Fly   255 IVRCAENWGLSTLQAEIPSYMNGVLDMDMKSNAFFSALPFLAMWCMSYIYLVVADVLLGKNSVSL 319
            :.....:|....|....|:|...|...::......||:|.|.|..:..|...:||.|..|..:|.
Mouse   317 VANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSKQILST 381

  Fly   320 TILRKTYNSIAFWIPAATLVGIGFLDKEQKNFAIALMTISVGVNSAQTIGSVLNTIDLSKNHASI 384
            |.:||..|...|.:.|..|:.:|:  ...:..||:.:.::||.:.....|..:|.:|::..:|||
Mouse   382 TTVRKIMNCGGFGMEATLLLVVGY--SHTRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASI 444

  Fly   385 LMGIVNTAANFVPIVTPLVVGWIVKENSDRSQWQIVFIIASVIFFVGNCIYLVFGTAETQPW-DA 448
            ||||.|.......:|.|::||.:.| |..|.:||.||:||:::.:.|...|.:|.:.|.||| |.
Mouse   445 LMGISNGVGTLSGMVCPIIVGAMTK-NKSREEWQYVFLIAALVHYGGVIFYALFASGEKQPWADP 508

  Fly   449 ED 450
            |:
Mouse   509 EE 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9825	NP_611723.3	2A0114euk	14..450	CDD:129972	141/452 (31%)
CG9825	NP_611723.3	MFS	54..438	CDD:119392	123/393 (31%)
Slc17a6	NP_543129.3	2A0114euk	70..511	CDD:129972	142/454 (31%)
Slc17a6	NP_543129.3	MFS	75..498	CDD:119392	133/435 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I11710
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810