DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9825 and Slc17a7

DIOPT Version :9

Sequence 1:	NP_611723.3	Gene:	CG9825 / 37624	FlyBaseID:	FBgn0034783	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	XP_038966881.1	Gene:	Slc17a7 / 116638	RGDID:	620101	Length:	585	Species:	Rattus norvegicus

Alignment Length:	529	Identity:	155/529 - (29%)
Similarity:	237/529 - (44%)	Gaps:	76/529 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTAETNKGPV-------LGMRHVQALLIFLNITTVFIGRLNVGVSVVAMTNAETTN--------- 49
            :|..|...||       |..|::.|::..|.....|..|.|:||::|:|.|..||:
  Rat    42 VTTHTRDPPVVDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTTHRGGHVVVQT 106

  Fly    50 ------------PNF----------PEYDWTEAEKSYILSSFFWGYILTQFLGGYLCKRFGVKSV 92
                        |..          .:::|.......|..|||||||:||..||::|::|....|
  Rat   107 PYRSVHKQEAVTPTVGDIQGGDTEKAQFNWDPETVGLIHGSFFWGYIVTQIPGGFICQKFAANRV 171

  Fly    93 MFWGVFGSGVCSALTP--LFIGFGEWQAYCGI--RVLMGLAQGVVFPCIHQHLAKWSPPEERNRL 153
            ..:.:..:...:.|.|  ..:.:|     |.|  |:|.||.:||.:|..|...:||:||.||:||
  Rat   172 FGFAIVATSTLNMLIPSAARVHYG-----CVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRL 231

  Fly   154 GALSHTGIECGNVSAMFLSGMIAKSSLGWPGISYVSAGVAFFWCTLWFVFAANHPTESRFIGENE 218
            ...:..|...|.|.||.|:|::.:.| ||..:.||......||...|.:.:...|.....|.|.|
  Rat   232 ATTAFCGSYAGAVVAMPLAGVLVQYS-GWSSVFYVYGSFGIFWYLFWLLVSYESPALHPSISEEE 295

  Fly   219 LIYIESSLKHNESY--HATIIPIPWKAIWTSAPFLALLIVRCAENWGLSTLQAEIPSYMNGVLDM 281
            ..|||.::..:...  ..|....||:..:||.|..|:::.....:|....|....|:|...|...
  Rat   296 RKYIEDAIGESAKLMNPVTKFNTPWRRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGF 360

  Fly   282 DMKSNAFFSALPFLAMWCMSYIYLVVADVLLGKNSVSLTILRKTYNSIAFWIPAATLVGIGFLDK 346
            ::......||||.|.|..:..|...:||.|..::.:|.|.:||..|...|.:.|..|:.:|:  .
  Rat   361 EISKVGLVSALPHLVMTIIVPIGGQIADFLRSRHIMSTTNVRKLMNCGGFGMEATLLLVVGY--S 423

  Fly   347 EQKNFAIALMTISVGVNSAQTIGSVLNTIDLSKNHASILMGIVNTAANFVPIVTPLVVGWIVKEN 411
            ..|..||:.:.::||.:.....|..:|.:|::..:|||||||.|.......:|.|::||.:.|..
  Rat   424 HSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKHK 488

  Fly   412 SDRSQWQIVFIIASVIFFVGNCIYLVFGTAETQPWDAEDYLQTQNPELANRPPMQALSFPINENS 476
            : |.:||.||:|||::.:.|...|.||.:.|.||| ||       ||               |.|
  Rat   489 T-REEWQYVFLIASLVHYGGVIFYGVFASGEKQPW-AE-------PE---------------EMS 529

  Fly   477 KEKINSKSH 485
            :||.....|
  Rat   530 EEKCGFVGH 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9825	NP_611723.3	2A0114euk	14..450	CDD:129972	142/472 (30%)
CG9825	NP_611723.3	MFS	54..438	CDD:119392	121/389 (31%)
Slc17a7	XP_038966881.1	MFS_SLC17A6_7_8_VGluT	66..515	CDD:340940	135/457 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342472
Domainoid	1	1.000	47	1.000	Domainoid score	I11657
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.850