DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9825 and slc17a6b

DIOPT Version :9

Sequence 1:	NP_611723.3	Gene:	CG9825 / 37624	FlyBaseID:	FBgn0034783	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001122293.1	Gene:	slc17a6b / 100149756	ZFINID:	ZDB-GENE-030616-554	Length:	584	Species:	Danio rerio

Alignment Length:	481	Identity:	152/481 - (31%)
Similarity:	229/481 - (47%)	Gaps:	39/481 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 AETN--KGPV-------LGMRHVQALLIFLNITTVFIGRLNVGVSVVAMTNAETTNPN------- 51
            |:.|  |.|:       |..|::.|::..|.....|..|.|:||::|:|.|..|.:.|
Zfish    49 AQINERKAPLCDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTIHLNGKIIIKE 113

  Fly    52 FPEYDWTEAEKSYILSSFFWGYILTQFLGGYLCKRFGVKSVMFWGVFGSGVCSALT-PLFI---G 112
            ..:::|.......|..|||||||:||..|||:..|.....     |||:.:....| .:||   .
Zfish   114 KAKFNWDPETVGLIHGSFFWGYIVTQIPGGYISSRLAANR-----VFGAAILLTSTLNMFIPSAA 173

  Fly   113 FGEWQAYCGIRVLMGLAQGVVFPCIHQHLAKWSPPEERNRLGALSHTGIECGNVSAMFLSGMIAK 177
            .|.:.....:|:|.||.:||.:|..|...:||:||.||:||...|..|...|.|.||.|:|::.:
Zfish   174 RGHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQ 238

  Fly   178 SSLGWPGISYVSAGVAFFWCTLWFVFAANHPTESRFIGENELIYIESSLKHNESY--HATIIPIP 240
            .: ||..:.||......||...|.:.:...|.|...|...|..|||.|:..:...  .|.....|
Zfish   239 YT-GWSSVFYVYGCFGIFWYMFWILVSYESPAEHPTITAEERCYIEESIGESAKLLGPADKFKTP 302

  Fly   241 WKAIWTSAPFLALLIVRCAENWGLSTLQAEIPSYMNGVLDMDMKSNAFFSALPFLAMWCMSYIYL 305
            |:..:||.|..|:::.....:|....|....|:|...|...::......||||.|.|..:..|..
Zfish   303 WRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSALPHLVMTIIVPIGG 367

  Fly   306 VVADVLLGKNSVSLTILRKTYNSIAFWIPAATLVGIGFLDKEQKNFAIALMTISVGVNSAQTIGS 370
            .:||.|..||.:|.|.:||..|...|.:.|..|:.:|:  ...|..||:.:.::||.:.....|.
Zfish   368 QLADHLRSKNILSTTTVRKIMNCGGFGMEATLLLIVGY--SHSKGVAISFLVLAVGFSGFAISGF 430

  Fly   371 VLNTIDLSKNHASILMGIVNTAANFVPIVTPLVVGWIVKENSDRSQWQIVFIIASVIFFVGNCIY 435
            .:|.:|::..:|||||||.|.......:|.||:||.:.|..: |.:||.||:|||::.:.|...|
Zfish   431 NVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKT-REEWQYVFLIASLVHYGGVIFY 494

  Fly   436 LVFGTAETQPWDAEDYLQTQNPELAN 461
            .:|.:.|.|||        .:|||.:
Zfish   495 GIFASGEKQPW--------ADPELTS 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9825	NP_611723.3	2A0114euk	14..450	CDD:129972	144/448 (32%)
CG9825	NP_611723.3	MFS	54..438	CDD:119392	126/389 (32%)
slc17a6b	NP_001122293.1	2A0114euk	69..509	CDD:129972	144/456 (32%)
slc17a6b	NP_001122293.1	MFS	74..498	CDD:119392	137/432 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	42	1.000	Domainoid score	I12425
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820