Protein Alignment CG12490 and tsgA

DIOPT Version :10

• Sequence 1: NP_611722.2
• Gene: CG12490 / 37623
• FlyBaseID: FBgn0034782
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_417823.1
• Gene: tsgA / 947869
• ECOCYCID: EG11262
• Length: 393
• Species: Escherichia coli
• Alignment Length: 448
• Identity: 100/448 - (22%)
• Similarity: 166/448 - (37%)
• Gaps: 133/448 - (29%)

  Fly    48 TNPNFPEYDWTEAEKSYIFSSFFWGYILTQFIGGYLCKRF----------------GVKSVMFWG 96
            ||.|..:..|. :..||..:...  .|:|..:.|.:...|                |:...:|..
E. coli     2 TNSNRIKLTWI-SFLSYALTGAL--VIVTGMVMGNIADYFNLPVSSMSNTFTFLNAGILISIFLN 63

  Fly    97 VFVSGVCSALTPLFIGFGGWQAYCGIRVVMGLAQGLVFPCIHHHLAKWSPPAERNRLGALSHTGM 161
            .::..:....|.|..||        :.:|:.:| ||:|   .|.||.:|  |....||.:|...|
E. coli    64 AWLMEIVPLKTQLRFGF--------LLMVLAVA-GLMF---SHSLALFS--AAMFILGVVSGITM 114

  Fly   162 ECGN--VSAMF-----------------LSGMIAKSAIGWPGISYVSAGLAFAWCAIWFVFAADN 207
            ..|.  |:.|:                 ::|||      :|.|:......:..|   ::|:|...
E. coli   115 SIGTFLVTQMYEGRQRGSRLLFTDSFFSMAGMI------FPMIAAFLLARSIEW---YWVYACIG 170

  Fly   208 AVESRYITQEELHY---IESSLKHNEDYHKTVIPV---PWMAIWTSAPFLALTLTRCCATWGLST 266
            .|   |:....|.:   ..:..||..   ||..||   .|     ....|.|::...|...|...
E. coli   171 LV---YVAIFILTFGCEFPALGKHAP---KTDAPVEKEKW-----GIGVLFLSVAALCYILGQLG 224

  Fly   267 LQAQIPTYMNGVLDMDMK------SNAFFSALPFLAMWIMSYVYLIIADV-----LLAGNRLSLT 320
            ..:.:|.|..| |.|.:.      ||.:.|.:  :.||..|:: |...|:     :|||    |.
E. coli   225 FISWVPEYAKG-LGMSLNDAGTLVSNFWMSYM--VGMWAFSFI-LRFFDLQRILTVLAG----LA 281

  Fly   321 A-LRKTFNS-----LAFWIPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGSSLNTIDLSP 379
            | |...||:     :| |    :::.:||...       |:.|..:      |:||....:. ||
E. coli   282 AILMYVFNTGTPAHMA-W----SILALGFFSS-------AIYTTII------TLGSQQTKVP-SP 327

  Fly   380 NHASILMGILNTAVTVVPIVTPLIVGVIVHEDDNRAE-------WQIVFIIAAVLFFV 430
            .    |:..:.|..|:..::|.::.|.||.....:|.       :.:||::..:|.||
E. coli   328 K----LVNFVLTCGTIGTMLTFVVTGPIVEHSGPQAALLTANGLYAVVFVMCFLLGFV 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12490	NP_611722.2	MFS_SLC17	18..439	CDD:340876	100/448 (22%)
tsgA	NP_417823.1	PRK03699	2..393	CDD:235151	100/448 (22%)