Protein Alignment CG12490 and slc17a7a

DIOPT Version :10

• Sequence 1: NP_611722.2
• Gene: CG12490 / 37623
• FlyBaseID: FBgn0034782
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_001092225.1
• Gene: slc17a7a / 795293
• ZFINID: ZDB-GENE-050105-5
• Length: 582
• Species: Danio rerio
• Alignment Length: 456
• Identity: 145/456 - (31%)
• Similarity: 223/456 - (48%)
• Gaps: 28/456 - (6%)

  Fly    11 LGMRHVQALLIFLNITTVFIGRLNVGVSVVAMTNAETTNPN------FPEYDWTEAEKSYIFSSF 69
            |..|::.|:|..|.....|..|.|:||::|:|.|..|....      ..::.|.......|..||
Zfish    59 LPRRYIIAILSGLGFCISFGIRCNLGVAIVSMVNDHTVYSGKKPVIVAAQFTWDPETVGMIHGSF 123

  Fly    70 FWGYILTQFIGGYLCKRFGVKSVMFWGVFVSGVCSALTPLFIGFGGWQAYCG----IRVVMGLAQ 130
            |||||:||..||::|::|....|..:.:..:...:.|.|     ...:.:.|    :||..||.:
Zfish   124 FWGYIVTQIPGGFICQKFAANRVFGFAIVATSTLNMLIP-----SAARVHYGCVIMVRVCQGLVE 183

  Fly   131 GLVFPCIHHHLAKWSPPAERNRLGALSHTGMECGNVSAMFLSGMIAKSAIGWPGISYVSAGLAFA 195
            |:.:|..|...|||:||.||:||...:..|...|.|.||.|:|::.:.. ||..:.||...:...
Zfish   184 GVSYPACHGIWAKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQYT-GWSSVFYVYGSVGIF 247

  Fly   196 WCAIWFVFAADNAVESRYITQEELHYIESSLKHNEDYHKTVIPV-----PWMAIWTSAPFLALTL 255
            |...|.:.:.::......||.||..|||.::..:..   .|.|:     ||...:||.|..|:.:
Zfish   248 WYLFWILVSYESPAAHPTITPEERKYIEDAIGESAG---LVNPLQKFKTPWRHFFTSMPVYAIIV 309

  Fly   256 TRCCATWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIADVLLAGNRLSLT 320
            ...|.:|....|....|.|...|...::......||||.|.|.|:..:...:||.|...|.::.|
Zfish   310 ANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMVSALPHLVMTIIVPIGGQLADYLRTHNLMTTT 374

  Fly   321 ALRKTFNSLAFWIPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGSSLNTIDLSPNHASIL 385
            .:||..|...|.:....|:.:||  ...|.:||:.:.::||.:..|..|.::|.:|::|.:||||
Zfish   375 NVRKLMNCGGFGMEATLLLVVGF--SHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASIL 437

  Fly   386 MGILNTAVTVVPIVTPLIVGVIVHEDDNRAEWQIVFIIAAVLFFVGNSVYLYFGTAVSQPW-DAE 449
            |||.|...|:..:|.|||||.:. :...|.|||.||:|||::.:.|...|..|.:...||| |||
Zfish   438 MGISNGVGTLSGMVCPLIVGAMT-KHKTREEWQYVFLIAALVHYGGVIFYGLFASGEKQPWADAE 501

  Fly   450 D 450
            :
Zfish   502 N 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12490	NP_611722.2	MFS_SLC17	18..439	CDD:340876	136/435 (31%)
slc17a7a	NP_001092225.1	MFS_SLC17A6_7_8_VGluT	66..490	CDD:340940	136/435 (31%)