DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12490 and slc17a5

DIOPT Version :9

Sequence 1:	NP_611722.2	Gene:	CG12490 / 37623	FlyBaseID:	FBgn0034782	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_001072823.1	Gene:	slc17a5 / 780284	XenbaseID:	XB-GENE-853687	Length:	496	Species:	Xenopus tropicalis

Alignment Length:	472	Identity:	154/472 - (32%)
Similarity:	238/472 - (50%)	Gaps:	36/472 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KGPV-LGMRHVQALLIFLNITTVFIGRLNVGVSVVAMTNAETT---------------------N 49
            |.|| ...|:..||:..|....::..|:|:.|::|.|.|:.:|                     |
Frog    32 KVPVCCSARYNLALMALLGFFMLYALRVNLSVALVDMVNSTSTPRENTTANICPDHTSAPAVLHN 96

  Fly    50 PNFPEYDWTEAEKSYIFSSFFWGYILTQFIGGYLCKRFGVKSVMFWGVFVSGVCSALTPLFIGFG 114
            ....:|||....:.:|..|||:||||||..|||:..:.|.|.::.:|:..:.|.:.||||...||
Frog    97 STGQKYDWDANTQGWILGSFFYGYILTQIPGGYVAGKIGGKQLLGFGILGTAVFTLLTPLAADFG 161

  Fly   115 GWQAYC--GIRVVMGLAQGLVFPCIHHHLAKWSPPAERNRLGALSHTGMECGNVSAMFLSGMIAK 177
               |.|  .:|.:.||.:|:.||.:|...|:|:||.||:||.:||:.|.:.|.|.::.:||:|.
Frog   162 ---AGCLIAVRALEGLGEGVTFPAMHAMWARWAPPLERSRLLSLSYAGAQLGTVVSLPVSGLIC- 222

  Fly   178 SAIGWPGISYVSAGLAFAWCAIWFVFAADNAVESRYITQEELHYIESSLKHNEDYHKTVIPVPWM 242
            ..:.|..:.|:...|...|..:|....:|.....|.||..|..||..:|::...|.|:   ||..
Frog   223 YYMDWIYVFYIFGTLGVLWFIMWCFLVSDTPQSHRSITDSEKEYILYTLQNQLSYRKS---VPCC 284

  Fly   243 AIWTSAPFLALTLTRCCATWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLII 307
            |:..|.|..|:.:......|...||...:||||..:|..:.:.|.|.||||:|..|:...:..:|
Frog   285 AMMKSLPLWAIIVAHFSYNWTFYTLLTLLPTYMKEILRFNAQENGFLSALPYLGCWVFMIMAGVI 349

  Fly   308 ADVLLAGNRLSLTALRKTFNSLAFWIPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGSSL 372
            ||.|.....:|...:||.||:|....|...|:..|:..... :||:..:|:|..:...:..|..:
Frog   350 ADCLREKLNISTKVVRKIFNTLGMLGPAIFLLAAGYTGCNY-SLAVVFLTLSTTLGGFSVAGYGI 413

  Fly   373 NTIDLSPNHASILMGILNTAVTVVPIVTPLIVGVIVHEDDNRAE-WQIVFIIAAVLFFVGNSVYL 436
            |.:|::|:.|.:|:||.||..|:..:|.|:|...:.|  ||..| |||||.|||.:.|.|...::
Frog   414 NHLDIAPSFAGLLLGITNTFATIPGMVGPVIAKALTH--DNTVEQWQIVFYIAAAINFFGAIFFI 476

  Fly   437 YFGTAVSQPWDAEDYLT 453
            .|.:...|.| |.|:.|
Frog   477 IFASGNVQDW-AVDHNT 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12490	NP_611722.2	2A0114euk	14..450	CDD:129972	149/459 (32%)
CG12490	NP_611722.2	MFS	54..438	CDD:119392	133/386 (34%)
slc17a5	NP_001072823.1	MFS_SLC17A5	43..466	CDD:340939	141/432 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D619250at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010