DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12490 and slc17a7

DIOPT Version :9

Sequence 1:	NP_611722.2	Gene:	CG12490 / 37623	FlyBaseID:	FBgn0034782	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_001072608.1	Gene:	slc17a7 / 780064	XenbaseID:	XB-GENE-5742677	Length:	576	Species:	Xenopus tropicalis

Alignment Length:	482	Identity:	147/482 - (30%)
Similarity:	228/482 - (47%)	Gaps:	31/482 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ETNKGPV-------LGMRHVQALLIFLNITTVFIGRLNVGVSVVAMTNAETTNP------NFPEY 55
            |..:.||       |..|::.|::..|.....|..|.|:||::|:|.|..|...      ...::
Frog    45 EEKRQPVVDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNNTVYKGNKIVIEQAQF 109

  Fly    56 DWTEAEKSYIFSSFFWGYILTQFIGGYLCKRFGVKSVMFWGVFVSGVCSALTPLFIGFGGWQAYC 120
            .|.......|..|||||||:||..|||:|::|....|..:.:..:...:.|.|...........|
Frog   110 TWDPETVGMIHGSFFWGYIVTQIPGGYICQKFAANRVFGFAIVATSTLNMLIPSAARVHFACVIC 174

  Fly   121 GIRVVMGLAQGLVFPCIHHHLAKWSPPAERNRLGALSHTGMECGNVSAMFLSGMIAKSAIGWPGI 185
             :|::.||.:|:.:|..|...:||:||.||:||...:..|...|.|.||.|:|::.:.: ||..:
Frog   175 -VRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQYS-GWSSV 237

  Fly   186 SYVSAGLAFAWCAIWFVFAADNAVESRYITQEELHYIESSLKHNEDYHKTV--IPVPWMAIWTSA 248
            .||.......|...|.:.:.::......|::||..|||.|:..:......:  ...||...:||.
Frog   238 FYVYGSFGIMWYMFWILVSYESPAIHPTISEEEKKYIEESIGESTGLMNPMAKFKAPWRKFFTSM 302

  Fly   249 PFLALTLTRCCATWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIADVLLA 313
            |..|:.:...|.:|....|....|.|...|...::......||||.|.|.|:..:...|||.|..
Frog   303 PVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLLSALPHLVMTIIVPIGGQIADFLRT 367

  Fly   314 GNRLSLTALRKTFNSLAFWIPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGSSLNTIDLS 378
            ...:|.|.:||..|...|.:....|:.:|:  ...:.:||:.:.::||.:..|..|.::|.:|::
Frog   368 KRIMSTTNVRKMMNCGGFGMEATLLLVVGY--SHSRGVAISFLVLAVGFSGFAISGFNVNHLDIA 430

  Fly   379 PNHASILMGILNTAVTVVPIVTPLIVGVIVHEDDNRAEWQIVFIIAAVLFFVGNSVYLYFGTAVS 443
            |.:|||||||.|...|:..:|.|||||.:. :...|.|||.||:||:::.:.|...|..|.:...
Frog   431 PRYASILMGISNGVGTLSGMVCPLIVGAMT-KHKTREEWQYVFLIASLVHYGGVLFYGIFASGEK 494

  Fly   444 QPWDAEDYLTVKVPELA---KVPAIHE 467
            ||| ||       ||..   |...|||
Frog   495 QPW-AE-------PEETSDEKCGFIHE 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12490	NP_611722.2	2A0114euk	14..450	CDD:129972	136/443 (31%)
CG12490	NP_611722.2	MFS	54..438	CDD:119392	119/385 (31%)
slc17a7	NP_001072608.1	2A0114euk	62..503	CDD:129972	139/453 (31%)
		MFS	67..490	CDD:119392	129/427 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	517..547
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910