Protein Alignment CG12490 and SLC17A6

DIOPT Version :9

• Sequence 1: NP_611722.2
• Gene: CG12490 / 37623
• FlyBaseID: FBgn0034782
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_065079.1
• Gene: SLC17A6 / 57084
• HGNCID: 16703
• Length: 582
• Species: Homo sapiens
• Alignment Length: 457
• Identity: 141/457 - (30%)
• Similarity: 223/457 - (48%)
• Gaps: 30/457 - (6%)

  Fly    11 LGMRHVQALLIFLNITTVFIGRLNVGVSVVAMTNAETTN------PNFPEYDWTEAEKSYIFSSF 69
            |..|::.|::..|.....|..|.|:||::|.|.|..|.:      ....:::|.......|..||
Human    67 LPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNWDPETVGMIHGSF 131

  Fly    70 FWGYILTQFIGGYLCKRFGVKSVMFWGVFVSGVCSALTPLFIGFGGWQAYCG----IRVVMGLAQ 130
            |||||:||..|||:..|.....|....:.::...:.|.|     ...:.:.|    :|::.||.:
Human   132 FWGYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIP-----SAARVHYGCVIFVRILQGLVE 191

  Fly   131 GLVFPCIHHHLAKWSPPAERNRLGALSHTGMECGNVSAMFLSGMIAKSAIGWPGISYVSAGLAFA 195
            |:.:|..|...:||:||.||:||...|..|...|.|.||.|:|::.:.. ||..:.||.......
Human   192 GVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYT-GWSSVFYVYGSFGMV 255

  Fly   196 WCAIWFVFAADNAVESRYITQEELHYIESSLKHNE------DYHKTVIPVPWMAIWTSAPFLALT 254
            |...|.:.:.::..:...||.||..|||.|:..:.      :..||    ||...:||.|..|:.
Human   256 WYMFWLLVSYESPAKHPTITDEERRYIEESIGESANLLGAMEKFKT----PWRKFFTSMPVYAII 316

  Fly   255 LTRCCATWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIADVLLAGNRLSL 319
            :...|.:|....|....|.|...|...::......||:|.|.|.|:..:...|||.|.:...||.
Human   317 VANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSKQILST 381

  Fly   320 TALRKTFNSLAFWIPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGSSLNTIDLSPNHASI 384
            |.:||..|...|.:....|:.:|:  ...:.:||:.:.::||.:..|..|.::|.:|::|.:|||
Human   382 TTVRKIMNCGGFGMEATLLLVVGY--SHTRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASI 444

  Fly   385 LMGILNTAVTVVPIVTPLIVGVIVHEDDNRAEWQIVFIIAAVLFFVGNSVYLYFGTAVSQPW-DA 448
            ||||.|...|:..:|.|:|||.:. ::.:|.|||.||:|||::.:.|...|..|.:...||| |.
Human   445 LMGISNGVGTLSGMVCPIIVGAMT-KNKSREEWQYVFLIAALVHYGGVIFYAIFASGEKQPWADP 508

  Fly   449 ED 450
            |:
Human   509 EE 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12490	NP_611722.2	2A0114euk	14..450	CDD:129972	139/452 (31%)
		MFS	54..438	CDD:119392	122/393 (31%)
SLC17A6	NP_065079.1	MFS_SLC17A6_7_8_VGluT	74..498	CDD:340940	133/436 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I11776
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.810