Protein Alignment CG12490 and SLC17A7

DIOPT Version :10

• Sequence 1: NP_611722.2
• Gene: CG12490 / 37623
• FlyBaseID: FBgn0034782
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_064705.1
• Gene: SLC17A7 / 57030
• HGNCID: 16704
• Length: 560
• Species: Homo sapiens
• Alignment Length: 465
• Identity: 140/465 - (30%)
• Similarity: 227/465 - (48%)
• Gaps: 28/465 - (6%)

  Fly     1 MTAETNKGPV-------LGMRHVQALLIFLNITTVFIGRLNVGVSVVAMTNAETTN------PNF 52
            :|.:|...||       |..|::.|::..|.....|..|.|:||::|:|.|..||:      ...
Human    42 VTTQTRDPPVVDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTTHRGGHVVVQK 106

  Fly    53 PEYDWTEAEKSYIFSSFFWGYILTQFIGGYLCKRFGVKSVMFWGVFVSGVCSALTPLFIGFGGWQ 117
            .::.|.......|..|||||||:||..||::|::|....|..:.:..:...:.|.|     ...:
Human   107 AQFSWDPETVGLIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAIVATSTLNMLIP-----SAAR 166

  Fly   118 AYCG----IRVVMGLAQGLVFPCIHHHLAKWSPPAERNRLGALSHTGMECGNVSAMFLSGMIAKS 178
            .:.|    :|::.||.:|:.:|..|...:||:||.||:||...:..|...|.|.||.|:|::.:.
Human   167 VHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQY 231

  Fly   179 AIGWPGISYVSAGLAFAWCAIWFVFAADNAVESRYITQEELHYIESSLKHNEDYHK--TVIPVPW 241
            : ||..:.||.......|...|.:.:.::......|::||..|||.::..:.....  |....||
Human   232 S-GWSSVFYVYGSFGIFWYLFWLLVSYESPALHPSISEEERKYIEDAIGESAKLMNPLTKFSTPW 295

  Fly   242 MAIWTSAPFLALTLTRCCATWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLI 306
            ...:||.|..|:.:...|.:|....|....|.|...|...::......||||.|.|.|:..:...
Human   296 RRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLVSALPHLVMTIIVPIGGQ 360

  Fly   307 IADVLLAGNRLSLTALRKTFNSLAFWIPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGSS 371
            |||.|.:...:|.|.:||..|...|.:....|:.:|:  ...|.:||:.:.::||.:..|..|.:
Human   361 IADFLRSRRIMSTTNVRKLMNCGGFGMEATLLLVVGY--SHSKGVAISFLVLAVGFSGFAISGFN 423

  Fly   372 LNTIDLSPNHASILMGILNTAVTVVPIVTPLIVGVIVHEDDNRAEWQIVFIIAAVLFFVGNSVYL 436
            :|.:|::|.:|||||||.|...|:..:|.|:|||.:. :...|.|||.||:||:::.:.|...|.
Human   424 VNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMT-KHKTREEWQYVFLIASLVHYGGVIFYG 487

  Fly   437 YFGTAVSQPW 446
            .|.:...|||
Human   488 VFASGEKQPW 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12490	NP_611722.2	MFS_SLC17	18..439	CDD:340876	130/432 (30%)
SLC17A7	NP_064705.1	MFS_SLC17A6_7_8_VGluT	66..490	CDD:340940	130/432 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	497..560		1/1 (100%)