DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12490 and NaPi-T

DIOPT Version :9

Sequence 1:	NP_611722.2	Gene:	CG12490 / 37623	FlyBaseID:	FBgn0034782	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_001260981.1	Gene:	NaPi-T / 36651	FlyBaseID:	FBgn0016684	Length:	524	Species:	Drosophila melanogaster

Alignment Length:	513	Identity:	135/513 - (26%)
Similarity:	226/513 - (44%)	Gaps:	72/513 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 MRHVQALLIFLNITTVFIG-------RLNVGVSVV-------AMTNAETTN-------------- 49
            |..|:|..:...:|  |||       |:|:.:::|       |:|:.||..
  Fly     1 MGQVEARTVLWYMT--FIGFIVNYMIRINLNITIVDMIAGKGAITSNETHENSTDLAALAEMNER 63

  Fly    50 ----------PNFP----EYDWTEAEKSYIFSSFFWGYILTQFIGGYLCKRFGVKSVMFWGVFVS 100
                      .|.|    .:.|.|.::..:..||||.:...|..||.|..::|.|.|..|...:.
  Fly    64 FSLERWFLDWANIPYEKNGFHWNEKQQGALLGSFFWAHWTLQIPGGILATKYGTKLVFGWSNGIG 128

  Fly   101 GVCSALTPLFIGFGGWQAYCG---IRVVMGLAQGLVFPCIHHHLAKWSPPAERNRLGALSHTGME 162
            ..|..|.|:.    .:.:|.|   :||..|...||.:|.:|...|||.||.||::. ..::.|..
  Fly   129 VFCCFLIPIV----SYWSYTGLIILRVFQGWITGLAWPSMHVLTAKWIPPNERSKF-VSAYLGSS 188

  Fly   163 CGNVSAMF--LSGMIAKSAIGWPGISYVSAGLAFAWCAIWFVFAADNAVESRYITQEELHYIESS 225
            .|  .|:|  :.|.|. ....|..:.|:...:...|...|.....|:..|...|...|..:||.|
  Fly   189 VG--VALFYPIFGYII-DWTRWEWVYYICGIVGTLWFIAWQFLVFDSPAEHPRIADSERKFIEKS 250

  Fly   226 LKHNEDYHKTVIPVPWMAIWTSAPFLALTLTRCCATWGLSTLQAQIPTYMNGVLDMDMKSNAFFS 290
            |..:....|.  |.||.||.||.|.....:.:....|||.||....|||...:...::::..|.|
  Fly   251 LGASIQGSKG--PTPWKAIATSRPVWLNVVAQWGGIWGLFTLMTHAPTYFRLIHHWNIRATGFLS 313

  Fly   291 ALPFLAMWIMSYVYLIIADVLLAGNRLSLTALRKTFNSLAFWIPCAT----LIGIGFLDQEQKNL 351
            .||.|...:.:||:.|.||.||..:::|.|.:||    ||.:|.|.|    ::.:.:... ....
  Fly   314 GLPHLMRMLFAYVFSIFADYLLRTDKMSRTNVRK----LATFICCGTKGLIVLALAYFGY-NATA 373

  Fly   352 AIALMTISVGVNSGATIGSSLNTIDLSPNHASILMGILNTAVTVVPIVTPLIVGVIVHEDDNRAE 416
            ||.|:|::..::...:.|...:.:|||||:|.|::|:......:...::|.|||.:.|.:.....
  Fly   374 AIVLVTVATMLHGAVSSGPLASMVDLSPNYAGIVLGVSGMIGGMPGFISPFIVGQLTHNNQTIDA 438

  Fly   417 WQIVFIIAAVLFFVGNSVYLYFGTAVSQPWDAEDYLTVKVPELAKVPAIHEAGKGIDD 474
            |:.||::.:::......:|:.|..:..|||::..:   ::|: :.:..:...|:..||
  Fly   439 WKNVFLLTSLMLTGSGILYVLFSESKLQPWNSGCH---QLPD-SGLKELQNLGRDQDD 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12490	NP_611722.2	2A0114euk	14..450	CDD:129972	130/486 (27%)
CG12490	NP_611722.2	MFS	54..438	CDD:119392	111/392 (28%)
NaPi-T	NP_001260981.1	2A0114euk	1..474	CDD:129972	131/492 (27%)
NaPi-T	NP_001260981.1	MFS	76..460	CDD:119392	112/398 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	8	7.960