DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12490 and CG3036

DIOPT Version :9

Sequence 1:	NP_611722.2	Gene:	CG12490 / 37623	FlyBaseID:	FBgn0034782	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster

Alignment Length:	492	Identity:	130/492 - (26%)
Similarity:	212/492 - (43%)	Gaps:	70/492 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 AETNKGPV------LGMRHVQALLIFLNITTVFIGRLNVGVSVVAM--------TNA-------- 45
            :.|.||.:      |..|.|..||..|.....:..|:|:.:::|.|        .||
  Fly     2 SNTEKGGLQRVRNFLSCRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNSTA 66

  Fly    46 --ETTNPN--------FPEYDWTEAEKSYIFSSFFWGYILTQFIGGYLCKRFGVKSVMFWGVFVS 100
              .|.:|:        ||   |...:.:::...||||||||:..||.|.:..|.:.|....:..:
  Fly    67 ANSTASPDGVDVYEERFP---WDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWA 128

  Fly   101 GVCSALTPLFIGFGGWQAYCGIRVVMGLAQGLVFPCIHHHLAKWSPPAERNRLGALSHTGMECGN 165
            .:.:.:|||.... .:.....:|||:|...|..:|.||...|.|.||.||::
  Fly   129 SLLTLITPLAAHI-NYVVLIVVRVVLGFMLGASWPAIHPVAAVWIPPMERSK------------- 179

  Fly   166 VSAMFLSGMIAK---------------SAIGWPGISYVSAGLAFAWCAIWFVFAADNAVESRYIT 215
                |:|.|:|.               |..||..:.|::..:...|...||.|..:.......|:
  Fly   180 ----FMSNMMASSLGAAITMPICGYLISVAGWASVFYLTGAVGLLWSLAWFTFVYETPATHPRIS 240

  Fly   216 QEELHYIESSLKHNEDYHKTVIPVPWMAIWTSAPFLALTLTRCCATWGLSTLQAQIPTYMNGVLD 280
            .||...||.::..... .|....|||..:..|....|:.:....|.:|..|:..|:||:|:.:|.
  Fly   241 AEERREIEEAIGTTTS-KKRPSHVPWGQLLCSPAVWAIIICHGLAVFGFFTVVNQLPTFMSKILH 304

  Fly   281 MDMKSNAFFSALPFLAMWIMSYVYLIIADVLLAGNRLSLTALRKTFNSLAFWIPCATLIGIGFLD 345
            .|:|.|..||:||:|..::|:.....:||.|.....||.||.||.|.:.|..||...:|...||.
  Fly   305 FDIKQNGLFSSLPYLGKYVMAVASSYLADYLRKKGTLSTTATRKLFTTFALVIPGLLMIVQVFLG 369

  Fly   346 QEQKNLAIALMTISVGVNSGATIGSSLNTIDLSPNHASILMGILNTAVTVVPIVTPLIVGVIVHE 410
            .: ...::.:.::::..:...|.|...|.:|::||....:.|:.||..:....::..:||.:.::
  Fly   370 YD-ATWSVTIFSLALFAHGAVTAGYLGNGLDIAPNFGGTIFGLANTLSSFGGFLSTSMVGALTYK 433

  Fly   411 DDNRAEWQIVFIIAAVLFFVGNSVYLYFGTAVSQPWD 447
            |.:...|||||.|.|..:.....|:...|:...|||:
  Fly   434 DQSFHSWQIVFWILAATYISAAVVFAILGSGELQPWN 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12490	NP_611722.2	2A0114euk	14..450	CDD:129972	126/475 (27%)
CG12490	NP_611722.2	MFS	54..438	CDD:119392	107/398 (27%)
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	126/475 (27%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	109/400 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	8	7.960