DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12490 and Slc17a2

DIOPT Version :9

Sequence 1:	NP_611722.2	Gene:	CG12490 / 37623	FlyBaseID:	FBgn0034782	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	XP_038951630.1	Gene:	Slc17a2 / 306950	RGDID:	1308821	Length:	487	Species:	Rattus norvegicus

Alignment Length:	478	Identity:	131/478 - (27%)
Similarity:	225/478 - (47%)	Gaps:	54/478 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 MRHVQALLIFLNITTVFIGRLNVGVSVVAM---------TNAETTNP-------------NFPE- 54
            :|:..||::..:..|:...|:::.::::||         .||....|             :|..
  Rat    25 LRYALALVMHFSNFTMITQRVSLSIAIIAMVNSTQHQDPANASAEGPVMNLLSNRSRGIKDFSTR 89

  Fly    55 ---YDWTEAEKSYIFSSFFWGYILTQFIGGYLCKRFGVKSVMFWGVFVSGVCSALTPLFIGFGGW 116
               |.|:...:..||||..:|.|||....|||...||.|.::..|:.:|.:.:..|||...||..
  Rat    90 AAVYQWSTETQGIIFSSISYGIILTLIPSGYLAGIFGAKQILGAGLLISSLLTLFTPLAADFGVI 154

  Fly   117 QAYCGIRVVMGLAQGLVFPCIHHHLAKWSPPAERNRLGALSHTGMECGNVSAMFLSGMIAKSAIG 181
            .... ||.|.|:|||:.:.......|||:||.||::|.:::.:|...|:...:.:.|:|:: |:|
  Rat   155 LVIV-IRTVQGMAQGMSWTGQFTIWAKWAPPLERSKLTSIAGSGAAFGSFIILCVGGLISQ-ALG 217

  Fly   182 WPGISYVSAGLAFAWCAIWFVFAADNAVESRYITQEELHYIESSLKHNEDYHKTVIPVPWMAIWT 246
            ||.|.|:...:....|.:||....|:.:....|:.:|..||.||:.......:..||:.
  Rat   218 WPFIFYIFGSIGCVCCVLWFTMIYDDPMHHPCISVKEKEYITSSVAQQSSSPRRSIPIK------ 276

  Fly   247 SAPFLALTLTRCCATWGL-----------STLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIM 300
                   .:.||...|.:           :.:...:|||::.||.::::.:...|:|||:|....
  Rat   277 -------AMVRCLPLWAIFMGFFSHFWLCTIIITYLPTYISTVLHVNIRDSGVLSSLPFIAASSC 334

  Fly   301 SYVYLIIADVLLAGNRLSLTALRKTFNSLAFWIPCATLIGIGFLDQEQKNLAIALMTISVGVNSG 365
            :.:...:||.||:.|.|||..:||.|:||...:|....:.:.|:.... ...|.|:.:..|.::.
  Rat   335 TILGGQMADFLLSRNLLSLITVRKLFSSLGLLLPSLCAVALPFVTSSY-IATIVLLILIPGTSNL 398

  Fly   366 ATIGSSLNTIDLSPNHASILMGILNTAVTVVPIVTPLIVGVIVHEDDNRAEWQIVFIIAAVLFFV 430
            ...|..:||:|::|.:||.||||.........|::....|.::.: |:.:.|:.||.::|.:...
  Rat   399 CDSGFIINTLDVAPRYASFLMGISRGFGLTAGIISSTTTGFLISQ-DSESGWRNVFFLSAAVNMF 462

  Fly   431 GNSVYLYFGTAVSQPWDAEDYLT 453
            |...||.||.|..|.|..|..||
  Rat   463 GLIFYLIFGQAEIQNWAKERTLT 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12490	NP_611722.2	2A0114euk	14..450	CDD:129972	128/472 (27%)
CG12490	NP_611722.2	MFS	54..438	CDD:119392	112/398 (28%)
Slc17a2	XP_038951630.1	MFS_SLC17	30..471	CDD:340876	122/457 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342558
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740