Protein Alignment CG12490 and Slc17a8

DIOPT Version :9

• Sequence 1: NP_611722.2
• Gene: CG12490 / 37623
• FlyBaseID: FBgn0034782
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_714947.1
• Gene: Slc17a8 / 266767
• RGDID: 628870
• Length: 588
• Species: Rattus norvegicus
• Alignment Length: 473
• Identity: 143/473 - (30%)
• Similarity: 227/473 - (47%)
• Gaps: 27/473 - (5%)

  Fly    14 RHVQALLIFLNITTVFIGRLNVGVSVVAMTNAETT----NPNF--PEYDWTEAEKSYIFSSFFWG 72
            |::.|::..|.....|..|.|:||::|.|.|..|.    .|..  .:::|.......|..|||||
  Rat    75 RYIIAVMSGLGFCISFGIRCNLGVAIVEMVNNSTVYVDGKPEIQTAQFNWDPETVGLIHGSFFWG 139

  Fly    73 YILTQFIGGYLCKRFGVKSVMFWGVFVSGVCSALTPLFIGFGGWQAYCG----IRVVMGLAQGLV 133
            ||:||..||::..:|....|....:|::...:...|     ...:.:.|    :|::.||.:|:.
  Rat   140 YIVTQIPGGFISNKFAANRVFGAAIFLTSTLNMFIP-----SAARVHYGCVMCVRILQGLVEGVT 199

  Fly   134 FPCIHHHLAKWSPPAERNRLGALSHTGMECGNVSAMFLSGMIAKSAIGWPGISYVSAGLAFAWCA 198
            :|..|...:||:||.||:||...|..|...|.|.||.|:|::.: .|||..:.|:.......|..
  Rat   200 YPACHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGVLVQ-YIGWASVFYIYGMFGIIWYM 263

  Fly   199 IWFVFAADNAVESRYITQEELHYIESSLKHNEDYHK-TVIPVPWMAIWTSAPFLALTLTRCCATW 262
            .|.:.|.:.......|:.||..|||:|:....:... :....||...:||.|..|:.:...|.:|
  Rat   264 FWLLQAYECPAVHPTISNEERTYIETSIGEGANLASLSKFNTPWRRFFTSLPVYAIIVANFCRSW 328

  Fly   263 GLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIADVLLAGNRLSLTALRKTFN 327
            ....|....|.|...|....:......||:|.:.|.|:..:...:||.|.:...|:.||:||..|
  Rat   329 TFYLLLISQPAYFEEVFGFAISKVGLLSAVPHMVMTIVVPIGGQLADYLRSRKILTTTAVRKIMN 393

  Fly   328 SLAFWIPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGSSLNTIDLSPNHASILMGILNTA 392
            ...|.:....|:.:||  ...|.:||:.:.::||.:..|..|.::|.:|::|.:|||||||.|..
  Rat   394 CGGFGMEATLLLVVGF--SHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGV 456

  Fly   393 VTVVPIVTPLIVGVIVHEDDNRAEWQIVFIIAAVLFFVGNSVYLYFGTAVSQPWDAEDYLT---- 453
            .|:..:|.|||||.:. :...|.|||.||:|||::.:.|...|..|.:...|.|...:.|:
  Rat   457 GTLSGMVCPLIVGAMT-KHKTREEWQNVFLIAALVHYSGVIFYGVFASGEKQDWADPENLSEEKC 520

  Fly   454 --VKVPELAKVPAI-HEA 468
              :...|||:...: |||
  Rat   521 GIIDQDELAEETELNHEA 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12490	NP_611722.2	2A0114euk	14..450	CDD:129972	136/446 (30%)
		MFS	54..438	CDD:119392	120/388 (31%)
Slc17a8	NP_714947.1	MFS_SLC17A6_7_8_VGluT	79..502	CDD:340940	132/431 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	539..588		143/473 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342510
Domainoid	1	1.000	47	1.000	Domainoid score	I11657
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.740