DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12490 and SPAC1039.04

DIOPT Version :9

Sequence 1:	NP_611722.2	Gene:	CG12490 / 37623	FlyBaseID:	FBgn0034782	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_594995.1	Gene:	SPAC1039.04 / 2542960	PomBaseID:	SPAC1039.04	Length:	507	Species:	Schizosaccharomyces pombe

Alignment Length:	462	Identity:	98/462 - (21%)
Similarity:	172/462 - (37%)	Gaps:	97/462 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 ALLIFLNITTVFIGRLNVGVSVVAMTNAETTNPNFPEYDWTEAEKSYIFSSFFWGYILTQFIGGY 82
            |||...|.    :.:.||       :||: ||....:..:...:.:.:.|.|:..::|..|...|
pombe    66 ALLYLFNA----LDKSNV-------SNAK-TNGMDKDLGFVGDQYNIMISIFYIPFVLCAFPFSY 118

  Fly    83 LCKRFGVKSVMFWGVFVSGVCSALTPLFIGFGGWQAYCGIRVVMGLAQGLVFPCIHHHLAKWSPP 147
            |.||||...::.:.:...|..|........|||..|   :|..:|:|:..|.|.:.::|..:...
pombe   119 LYKRFGAARILPFFMLSFGAMSLCQAAVKNFGGMMA---VRWFLGMAESAVLPGVVYYLTTFYRR 180

  Fly   148 AERNRLGALSHTGMECGNVSAMFLSGMIAKSAI--------GWPGISYVSAGLAFAWCAIWFVFA 204
            .|..|..|:.:.   ..|||:.| .|::|....        ||..:..:..|:.|. |||.....
pombe   181 TELARRLAIFYA---AANVSSAF-GGLLAYGVFHIKGGKLQGWQYLFLIEGGVTFL-CAIVIFLV 240

  Fly   205 ADNAVE-SRYITQEELHY----IES----------SLKHNEDYHKTVIPVPW----MAIWTSAPF 250
            ...:|| :.::|.||...    ||:          |.|.:....|..|.:.|    ||:......
pombe   241 LPVSVETANFLTDEEKTLAKMRIENDSSSAISEKLSFKQSLTVFKHPIAILWLLEEMALGVPLNS 305

  Fly   251 LALTLTRCCATWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIADVLLAGN 315
            :...|.:..|..|.|::...:.|....:..               |:|::  |:..|:|.|....
pombe   306 INNWLPQIVAAMGFSSVNTNLMTVAPAISG---------------AIWLL--VFAFISDFLKNRG 353

  Fly   316 RLSLTALRKTFNSLAFW--IPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGSSLNTI--- 375
            .:.:.|:..|......:  |.....||:.:       .|..|||      :||...|.|.:.
pombe   354 IVLIAAISTTMIGFIVYGSIDIMNHIGVSY-------FACFLMT------AGAAASSVLTSTWYN 405

  Fly   376 DLSPNHASILMGILNTAVTVVPIVTPLIVGVI---VHEDDNRAEWQIVFIIAA------VLFFVG 431
            :.:||.:.      ....|.|.:....::|::   :....:..::.....|.|      :|....
pombe   406 NNTPNESR------RAVFTSVGVPLANVMGLVSANIFRPQDAPKYVPALGITAGFGGLGILLVAS 464

  Fly   432 NSVYLYF 438
            .|||::|
pombe   465 ISVYMFF 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12490	NP_611722.2	2A0114euk	14..450	CDD:129972	98/462 (21%)
CG12490	NP_611722.2	MFS	54..438	CDD:119392	87/424 (21%)
SPAC1039.04	NP_594995.1	MFS	71..471	CDD:119392	94/455 (21%)
SPAC1039.04	NP_594995.1	2A0114	71..463	CDD:273326	91/447 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050