Protein Alignment CG12490 and SLC37A2

DIOPT Version :10

• Sequence 1: NP_611722.2
• Gene: CG12490 / 37623
• FlyBaseID: FBgn0034782
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_938018.1
• Gene: SLC37A2 / 219855
• HGNCID: 20644
• Length: 505
• Species: Homo sapiens
• Alignment Length: 451
• Identity: 89/451 - (19%)
• Similarity: 155/451 - (34%)
• Gaps: 132/451 - (29%)

  Fly    57 WTEAEK-SY------IFSSFFWGYILTQFIGGYLCKRFGVKSVMFWGVFVSGVCSALTPLFIGFG 114
            |...:| :|      :.::|...|.:..||.|...:|..::..:..|:.:||:   .|.|| |.|
Human    75 WAPFDKDNYKELLGGVDNAFLIAYAIGMFISGVFGERLPLRYYLSAGMLLSGL---FTSLF-GLG 135

  Fly   115 -GWQA-----YCGIRVVMGLAQGLVFPCIHHHLAKWSPPAERNRLGAL--SHTGMECGNVSAMFL 171
             .|..     :..|:|..||.|...:|.:...:..|....:|..:..:  |||.:  ||:....:
Human   136 YFWNIHELWYFVVIQVCNGLVQTTGWPSVVTCVGNWFGKGKRGFIMGIWNSHTSV--GNILGSLI 198

  Fly   172 SGMIAKSAIGWPGISYVSAGLAFA-WCAIWFVFAADNAVESRYITQEELHYIESSLKHN--EDYH 233
            :|:.....  | |:|::..|:..| ...|.|:|..::..:......:  |:.|.:...:  ||..
Human   199 AGIWVNGQ--W-GLSFIVPGIITAVMGVITFLFLIEHPEDVDCAPPQ--HHGEPAENQDNPEDPG 258

  Fly   234 KTVIPVPWMAIWTSAPFLALTLTRCCATWGLSTLQA-QIPTYMNGVLDMDMKSNAFFSALPFLAM 297
            .:...:....:.|.|   ..:...|.....:|...| :||    ||::.         :|..|..
Human   259 NSPCSIRESGLETVA---KCSKGPCEEPAAISFFGALRIP----GVVEF---------SLCLLFA 307

  Fly   298 WIMSYVYLIIADVLLAGNRLSLTALRKTFNSLAFWIPCATLIGIGFLDQEQKNLAIALMTISVGV 362
            .::||.:|                         :|:|                |.||
Human   308 KLVSYTFL-------------------------YWLP----------------LYIA-------- 323

  Fly   363 NSGATIGSSLNTIDLSPNHASILMGILNTAVTVVPIVTPLIVGVIVHEDDNRA-EWQIVFIIAAV 426
                      |....|...|    |.|:|...|..|:..::.|::....:.|| ...::.|:||.
Human   324 ----------NVAHFSAKEA----GDLSTLFDVGGIIGGIVAGLVSDYTNGRATTCCVMLILAAP 374

  Fly   427 LFFVGNSV----------------------YLYFGTAVSQPWDAEDYLTVKVPELAKVPAI 465
            :.|:.|.:                      |....||||........|......|:.|.||
Human   375 MMFLYNYIGQDGIASSIVMLIICGGLVNGPYALITTAVSADLGTHKSLKGNAKALSTVTAI 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12490	NP_611722.2	MFS_SLC17	18..439	CDD:340876	80/423 (19%)
SLC37A2	NP_938018.1	MFS_SLC37A1_2	22..484	CDD:340902	89/451 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..262		4/23 (17%)