Protein Alignment CG12490 and D1046.4

DIOPT Version :10

• Sequence 1: NP_611722.2
• Gene: CG12490 / 37623
• FlyBaseID: FBgn0034782
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_501553.2
• Gene: D1046.4 / 183909
• WormBaseID: WBGene00008365
• Length: 568
• Species: Caenorhabditis elegans
• Alignment Length: 542
• Identity: 93/542 - (17%)
• Similarity: 195/542 - (35%)
• Gaps: 141/542 - (26%)

  Fly     1 MTAETNKGPVLG------------------MRHVQALLIFLNITTVFIGRLNVGVSVVAMTNAET 47
            :||:..|.|:..                  .|.:..||:.|...||:...:.:..||:.|:..:.
 Worm     2 ITADNLKTPIFSATRCTNDHLPAYKSFLHRTRFLLLLLVILLNATVYSNTILINFSVICMSEEKI 66

  Fly    48 T---NPNFPEYD----------------W---TEAEKSYIFSSFFWGYILTQFIGGYLCKRFGVK 90
            :   |.:..:|:                |   :..::|.:|.....|.:|..:....|..:||.:
 Worm    67 STMFNGSHNDYEVLREAIATSMNDFRSIWFTFSSIKQSIMFMMSPLGSLLAMYPTWMLIMKFGYR 131

  Fly    91 SVMFWGVFVSGVCSALTP--LFIGFGGWQAYCGIRVVMGLAQGLVFPCIHHHLAKWSPPAERNRL 153
            .:......:|...:|..|  :|.|| .:.|.|  :.::|.........:...:.|||.....:..
 Worm   132 RICSTTCLISTFLTAFLPWSIFFGF-PYVATC--QFLLGATAPSALLLVPSVIRKWSTRKNDHFC 193

  Fly   154 GALSHTGMECGNVSAMFLSGMIAKSAIGWPGISYVSAGLAFAWCAIWFVFAADNAVESRYITQEE 218
            ..:..|..:....:...::..|:|:.:|||.|.|..:..:.....::|.|..:..:....::..|
 Worm   194 FLVLFTFQQISPAALYPIAAYISKTFVGWPVIFYFQSIFSCIVTTVFFYFYKETPIRHANVSDNE 258

  Fly   219 LHYIE--SSLKHNEDYHKTVIPVPWMAIWTSAPFLALTLTRCCATWGLSTLQAQIPTYMNGVLDM 281
            |..|:  .:::.|.||.|..:...:.::..|.....:|         .|.....:|:|:..:::.
 Worm   259 LQKIQRNEAVRGNIDYKKMFLCHQFQSVCFSIFIYFMT---------FSFFVQYLPSYLYDIMEQ 314

  Fly   282 DMKSNAFFSALPFLAMWIMSYVYLIIADVLLAGNRLSLTALRKTFNSLAFWIPCATLIGIGFLDQ 346
            .::..|          |.:|.:  ||..::|           |.|.|..|
 Worm   315 SVEKTA----------WTVSLI--IIVHLIL-----------KIFISRIF--------------- 341

  Fly   347 EQKNLAIALMTISVGVNSGATIGSS--LNTIDLSPNHASILMGILNTAVTV-------------- 395
            |:..|...:.:|.. :...:..||:  :.|:.::..|..|.: ||..|:..
 Worm   342 EKNPLLTNIYSIKF-LQFSSFAGSAVIMITLFVTKFHFDIQL-ILYAAIFAFLSLTWPSVFKSSN 404

  Fly   396 -------VPI-----------------VTPLIVGVIVHEDDNRAEWQIVFIIAAVLFFVGNSVYL 436
                   :|:                 :.||::|   ...::...|:.::::.|||..  .||.|
 Worm   405 IISNKYYLPVMVRIHVVLFYFGSFASNILPLVLG---RNTESWNNWRWIWLVFAVLLI--GSVIL 464

  Fly   437 YFGTAVSQPWDAEDYLTVKVPE 458
            ::.|...:..|.:..:.|:.|:
 Worm   465 FWLTFQFEKSDWDIVIPVEPPQ 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12490	NP_611722.2	MFS_SLC17	18..439	CDD:340876	84/486 (17%)
D1046.4	NP_501553.2	MFS	96..466	CDD:349949	73/426 (17%)