Protein Alignment CG12490 and C18D1.2

DIOPT Version :10

• Sequence 1: NP_611722.2
• Gene: CG12490 / 37623
• FlyBaseID: FBgn0034782
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_496174.2
• Gene: C18D1.2 / 182781
• WormBaseID: WBGene00007669
• Length: 478
• Species: Caenorhabditis elegans
• Alignment Length: 492
• Identity: 106/492 - (21%)
• Similarity: 201/492 - (40%)
• Gaps: 88/492 - (17%)

  Fly    13 MRH-VQALLIFLNITTVFIGR---LNVGVSVVAM--------TNAETTNPNFPE----------Y 55
            :|| .:..::||.:..:.|.:   |.:..:::.|        |.|...:.|..:          |
 Worm    10 IRHRTRFFILFLCLLCLSISQSNTLTLNFTIICMSTLHNFTATEASEKSTNVLDFMLHKILQKTY 74

  Fly    56 DWTEAEKSYIFSSFFWGYILTQFIGGYLCKRFGVKSVM-FWGVFVSGVCSALTPLFIGFGGWQAY 119
            .:|.::.:.:||:...|.:...:...|:.::.|.:||: |.|:| |...:|:.|       |.||
 Worm    75 VYTASQSNLLFSAVAIGAMCAVYPFMYIIQKKGSRSVVTFVGLF-SAATTAMIP-------WAAY 131

  Fly   120 CG------IRVVMGLAQGLVFPCIHHHLAKWSPPAERNRLGALSHTGMEC----GNVSAMFLSGM 174
            .|      :|.:.|:.....|..|.....:||...:    ||.....:.|    |.:..|.::..
 Worm   132 LGFYPLLAMRFLQGIGLSTGFTLIGIVTRQWSMQVQ----GAFFFACLSCFFQIGPIFTMPVASA 192

  Fly   175 IAKSAIGWPGISYVSAGLAFAWCAIWFVFAADNAVESRYITQEELHYIESSLKHNEDYHKTVI-- 237
            ...|:.|||.:.|..:.:......::|....::.|....:|:.||..|:......:.....::
 Worm   193 FCTSSFGWPAVYYTHSIVTIFIFLLFFTLYRESPVFHTIVTELELSKIQRGKGETKRQRVPLVQI 257

  Fly   238 ---PVPWMAIWTS--APFLALTLTRCCATWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAM 297
               ||. ::|||:  |.|:.:.||           ....|||::.:|...::....|||||.:
 Worm   258 LRDPVV-LSIWTTALANFMGIQLT-----------MQFTPTYLHKILGFSVQDTGPFSALPQV-- 308

  Fly   298 WIMSYVYLIIADVLLAGNRLSL----TALRKTFNSLAFWIPCATLIGIGFLDQEQKNLAIALMTI 358
             |.::|.:...   .:.::|..    |::| .|||||........:|:..:......|.:.::.:
 Worm   309 -ITAFVKVSAG---YSADKLQCCTPKTSVR-IFNSLALGGMSFMFVGLAIIPTSMPYLGLFMLIL 368

  Fly   359 S---VGVNSGATIGSSLNTIDLSPNHASILMGILNTAVTVVPIVTPLIVGVIVHEDDNRAEWQIV 420
            |   :|.|.|.....|   ...:..|...:||:.:....:..::.|:||.:.| |:|...||..|
 Worm   369 SCSIIGFNCGGFFRCS---AIYAAQHNHFVMGMNSFLNCLAALLAPVIVNIFV-ENDTWNEWYWV 429

  Fly   421 FIIAAVLFFVGNSVYLYFGTAVSQPWDAEDYLTVKVP 457
            ::...|:.|:.|.|:..:.......|      |.|.|
 Worm   430 WMSHFVILFLSNLVFQIYAKGEPAEW------TKKTP 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12490	NP_611722.2	MFS_SLC17	18..439	CDD:340876	100/466 (21%)
C18D1.2	NP_496174.2	MFS	36..448	CDD:475125	96/446 (22%)